ANEMIA

This study looks back at medical records to see if a specific class of heart failure drugs (SGLT2 inhibitors) helps improve blood cell production and, in turn, benefits heart and kidney health. It compares 85 patients who took these drugs to similar patients who did not, tracking…

This study is testing a new drug called INCB000928 to see if it can help people with a serious bone marrow cancer called myelofibrosis who have severe anemia. The drug will be tested alone and in combination with an existing medication, ruxolitinib. The main goals are to find a s…

This study is testing a new system designed to make donated red blood cells safer before they are given to patients who need transfusions. The system aims to reduce the risk of passing on infections like Zika virus through blood transfusions. The trial will compare the safety and…

This study provided emergency treatment for critically ill patients with dangerously low red blood cell counts who couldn't receive standard blood transfusions. It tested HBOC-201, an oxygen-carrying liquid made from purified cow hemoglobin, as a temporary substitute for blood. T…

This study is testing whether a drug called pazopanib can help people with hereditary hemorrhagic telangiectasia (HHT), a genetic disorder that causes frequent, severe nosebleeds and anemia. About 70 participants will take either pazopanib or a placebo pill daily for 24 weeks to …

This study is testing a drug called luspatercept to see if it is safe and effective for treating anemia in people with two specific blood disorders: myelodysplastic syndromes (MDS) or beta-thalassemia. The goal is to help patients who currently need regular red blood cell transfu…

This large, late-stage trial is comparing two treatment approaches for patients with a bone marrow disorder (MDS) and severe anemia. It tests whether a drug called lenalidomide works better alone or when combined with a hormone (epoetin alfa) that helps the body make red blood ce…

This large study is comparing two different treatment approaches for younger patients with a common type of blood cancer called chronic lymphocytic leukemia (CLL). One group receives a newer, targeted pill (ibrutinib) plus an antibody drug. The other group gets the standard, more…

This study is checking whether taking daily vitamin D or fish oil supplements can prevent anemia in older adults. It's part of a larger trial involving 2,000 participants who don't have anemia when they start. Researchers will track who develops anemia over time and measure blood…

This remote study aimed to provide holistic education and pastoral counseling to help people manage stress and improve wellness in daily life. It was designed for specific unmarried Alaska Medicaid recipients who met religious and lifestyle criteria. The study was withdrawn befor…

This study is testing a new iron supplement made from fish to see how well the body absorbs it and what stomach-related side effects it might cause. It involves 61 adult women who have low iron levels or mild anemia. Researchers will measure iron levels in the blood over 24 hours…

This study is measuring how a program that helps families escape poverty affects children's development, nutrition, and readiness for school. Researchers are following 2,100 children aged 0-9 in Uganda whose families were part of an earlier anti-poverty trial. The study is not te…

This study aims to understand how anemia (low red blood cells) and the blood transfusions used to treat it affect oxygen levels in the digestive systems of very small preterm babies. Researchers will observe 324 infants weighing 1250 grams or less to learn why some develop a seri…

This long-term study is observing over 1,300 children aged 8-10 in rural India to understand how they grow and develop. Researchers are tracking their height, weight, bone strength, and nutrition over many years, and will also follow them into adulthood to see how their health af…