ANEMIA

This study tested whether a combination of ibrutinib (a targeted drug) and rituximab works better than standard chemotherapy (FCR) for younger patients with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma. About 529 people took part. The main goal was t…

This phase 3 trial compares two treatments for people with a bone marrow disorder called myelodysplastic syndrome (MDS) who have low red blood cell counts (anemia). One group gets lenalidomide alone, the other gets lenalidomide plus epoetin alfa, a drug that stimulates red blood …

This study tests whether a package of school meals, vegetable gardens, nutrition classes, iron supplements, and deworming can reduce anemia and underweight in 1500 adolescents aged 14-17 in Tanzania. Four schools get the program, two serve as controls. Researchers will also inter…

This early-stage trial tests an experimental drug called INCB000928, given alone or with the standard drug ruxolitinib, for people with myelofibrosis who have severe anemia or need regular blood transfusions. The main goals are to check the drug's safety, find the right dose, and…

This study was designed to test a radioactive drug (177Lu-PSMA-617) in men with advanced prostate cancer that has spread to the bone marrow and caused low blood cell counts. The goal was to see if the treatment was safe and how it affected the cancer. However, the study was withd…

This study tests a drug called luspatercept in 6 adults with lower-risk myelodysplastic syndromes (MDS) or related blood cancers who have anemia. The goal is to see if the drug can reduce or eliminate the need for regular blood transfusions. Participants receive luspatercept plus…

This study tests whether giving pregnant women a daily vitamin B12 supplement (50 micrograms) from early pregnancy until six months after birth helps their children grow and think better. Researchers are enrolling 800 pregnant women in Nepal who are at risk of low B12 levels. The…

This study looks at whether a hormonal IUS or birth control pills with iron are better at improving anemia in women. About 405 women with mild to moderate anemia who want contraception will be randomly assigned to one of the two methods and followed for 12-18 months. The main goa…

This study tests a special treatment for red blood cells that aims to kill the Zika virus, making transfusions safer. About 692 people who need blood transfusions will receive either treated or standard blood. The goal is to see if the treated blood works just as well and is safe…

This study tests whether a low dose of pazopanib, a drug currently used for cancer, can reduce severe nosebleeds and improve anemia in people with hereditary hemorrhagic telangiectasia (HHT). About 70 participants will take either the drug or a placebo daily for 24 weeks. Researc…

This expanded access program tested HBOC-201 (Hemopure), a liquid oxygen carrier made from cow hemoglobin, in adults with life-threatening anemia who cannot receive blood transfusions. The goal was to improve oxygen delivery to tissues. Participants had very low hemoglobin levels…

This study tests a drug called luspatercept in people with anemia caused by myelodysplastic syndromes (MDS) or beta-thalassemia who need regular blood transfusions. The goal is to see if the drug is safe and can reduce the number of transfusions needed. About 85 participants in I…

This study tests whether a smartphone app can accurately detect anemia by analyzing images of the lower eyelid. The app uses artificial intelligence to estimate hemoglobin levels without a blood draw. Researchers will compare the app's results to standard lab tests in 3,000 adult…

This study tests a small, swallowable capsule called PillSense that can detect blood in the upper digestive tract within about 10 minutes. Researchers want to see if a negative result from the capsule can safely predict that a hospitalized patient with anemia or a positive stool …

This study looks at whether taking vitamin D and fish oil supplements can reduce the risk of developing anemia in people aged 60 and older. Researchers are following 2000 participants from a larger heart-health trial who did not have anemia at the start. They will compare anemia …

This study looks at how well a new iron supplement made from fish (SalmoFer®) is absorbed by the body and whether it causes stomach discomfort. About 61 women aged 21 to 42 with low iron or mild anemia will take the supplement and have their iron levels checked through blood test…

This study tests whether a tablet-based decision support system helps frontline health workers in India and Nepal provide better antenatal care. About 1,320 pregnant women will take part. The tool guides workers to check blood pressure, blood sugar, urine protein, and hemoglobin,…

This study examines whether SGLT2 inhibitors, a type of diabetes drug, can improve red blood cell production and heart/kidney function in people with chronic heart failure. Researchers will compare blood tests, heart ultrasound measures, and clinical outcomes between 85 patients …

This study was designed to test a holistic education program for stress management in people from colonized English-speaking countries. It aimed to help with conditions like stress, PTSD, anxiety, and fatigue using pastoral counseling and self-care activities. However, the study …

This study looks at how a program that helps families lift themselves out of poverty affects the growth and learning of children aged 0-9 in Uganda. Researchers will compare kids in families that received the program to those that did not, measuring things like height, anemia, th…

This study follows 1,304 healthy Indian adolescents aged 8–10 over time to see how their growth, bone health, and muscle development are linked to their parents' nutrition. Researchers aim to understand why malnutrition persists across generations and identify windows of opportun…