Cow-Hemoglobin drug offers hope for anemia patients who refuse blood

NCT ID NCT02684474

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This expanded access program tested HBOC-201 (Hemopure), a liquid oxygen carrier made from cow hemoglobin, in adults with life-threatening anemia who cannot receive blood transfusions. The goal was to improve oxygen delivery to tissues. Participants had very low hemoglobin levels and signs of organ distress. The treatment was given intravenously without needing blood type matching.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HBOC-201 (Hemopure), a lab-made oxygen carrier from cow hemoglobin

What this could lead to

If it works, this could provide a temporary oxygen-boosting option for severely anemic patients who cannot get blood transfusions, potentially saving lives in emergencies.

What could go wrong

This is an expanded access program, not a full trial, so data is limited. HBOC-201 may carry risks like high blood pressure or kidney issues, and it is not a substitute for blood in all cases.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States