Smarter transfusions: tailoring blood use after heart surgery

NCT ID NCT07671469

Not yet recruiting Disease control Sponsor: Yan Mia Min Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study compares two ways of deciding when heart surgery patients need a blood transfusion in the ICU. One uses a fixed blood count threshold, while the other also considers each patient's oxygen and lactate levels. The goal is to see if the personalized approach is as safe and reduces blood use. 900 adults at moderate-to-high surgical risk will participate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Personalized transfusion decision rule (a bedside tool using patient oxygen and lactate levels)
What this could lead to: If it works, this could lead to safer, more efficient blood use after heart surgery, reducing unnecessary transfusions while maintaining patient safety.
What could go wrong: This trial hasn't started yet, and the personalized approach may not prove as safe as the standard one. It's a comparison of existing strategies, not a new treatment.

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Conditions

The condition(s) this trial relates to.

anemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANEMIA BLOOD TRANSFUSION CARDIAC SURGERY CARDIOPULMONARY BYPASS

Contacts and locations

Locations

Stanford University Medical Center

Palo Alto, California, 94305, United States

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