ALCOHOL DRINKING

This study is testing whether a motivational chatbot app can help people who drink too much alcohol cut back. For four weeks, half of the 220 participants will use the app, while the other half waits. Researchers will compare how much alcohol each group drinks over 16 weeks to se…

This study is testing if a single dose of a nutritional ketone drink can help control alcohol use disorder. Researchers will measure if the drink changes brain activity in response to alcohol cues, reduces cravings, and leads to less drinking in a controlled setting. The study in…

This study is testing whether brief phone counseling from pharmacists can help people with HIV who drink alcohol and take multiple medications reduce their risk of falls and thinking problems. The program involves medication reviews, personalized risk discussions, and home alcoho…

This study is looking at whether an 8-week aerobic exercise program can help lower high blood pressure in middle-aged adults who binge drink. Researchers will compare blood pressure, small blood vessel function, and nerve activity in binge drinkers, moderate drinkers, and non-dri…

This study is testing a new interactive story app that uses artificial intelligence to help teenagers reduce risky alcohol use. The app, called CHANGEGRADIENTS, creates personalized stories where teens can explore the consequences of their choices in a virtual environment. Resear…

This small pilot study is exploring whether a combination of counseling to reduce alcohol use and taking a probiotic supplement can improve thinking skills and brain metabolism in older adults who are heavy drinkers. Researchers will measure changes in memory, attention, and how …

This study is testing personalized support programs to help people scheduled for elective surgery reduce their alcohol use. It aims to improve surgical recovery and promote long-term wellness. The program adapts its approach based on how participants are responding.

This study is testing new psychology-based programs designed to prevent binge drinking among university students. Researchers will enroll 240 students who report binge drinking to compare different counseling approaches. The goal is to see if combining motivational interviews wit…

This study is testing two technology-based programs designed to prevent or reduce alcohol misuse among teenagers. About 1,400 youth aged 12-19 who have drunk alcohol in the past year will either use a brief web-based program or that same program plus eight weeks of supportive tex…

This study is testing a phone-based therapy to help people living with HIV reduce unhealthy alcohol use and improve mental health. Researchers will compare a new therapy called Acceptance and Commitment Therapy (ACT) against a standard brief alcohol intervention. The goal is to s…

This study is testing if watching a short video of moving black and white squares can help reduce cravings for alcohol and how much people drink. Researchers are comparing this moving video to a still image in college students who drink alcohol and have cravings at least once a w…

This study aims to understand why young adults with bipolar disorder are at high risk for developing alcohol use disorders. Researchers will follow 160 young adults (half with bipolar disorder) for two years, using brain scans and controlled alcohol sessions to see how stress and…

This study aims to develop and test simple computer tasks that can be used during brain scans to better understand how alcohol use disorders affect behavior, thinking, and decision-making. Researchers are recruiting 400 adults, including both healthy volunteers and people with al…

This study aims to understand how a specific gene related to nicotine receptors influences a person's brain activity and behavior when exposed to alcohol. Researchers will recruit 128 healthy adults, including both smokers and non-smokers, to undergo brain scans and controlled al…

This study aims to understand how being in ketosis—through either a ketogenic diet or a ketone supplement drink—affects brain function and alcohol intoxication. Healthy adult participants will try three different 3-day diets, then have an MRI brain scan and drink alcohol to measu…

This study aims to understand how alcohol use disorder changes the brain. Researchers will use MRI brain scans and computer games to compare brain structure and function in adults with and without alcohol dependence. The goal is to link these brain differences to behavior, person…

This study aims to understand how the stress and isolation of the COVID-19 pandemic have affected people's alcohol use and related problems over time. Researchers will follow 1,500 participants for two years, asking them to complete regular surveys about their drinking, stress le…