Ketone supplements vs. alcohol: what happens inside your brain?

NCT ID NCT06815237

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how a single dose of a ketone supplement or an alcoholic drink changes brain metabolism compared to no drink. Sixty healthy adults who drink occasionally will have three MRI scans after each condition. The goal is to measure brain chemicals like NAD, glutamate, and GABA, not to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketone supplement (D-Beta-hydroxybutyric acid and R-1,3 butanediol) and alcohol beverage

What this could lead to

If successful, this could help scientists understand how ketones and alcohol change brain chemistry, possibly guiding future research on brain health.

What could go wrong

This is an early-stage study with only 60 participants, looking at short-term effects. Results may not apply to long-term use or to people with health conditions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alcohol Drinking Ketosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Studies of Addiction

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••