ALCOHOL DRINKING

This study tests different ways to help people drink less alcohol before and after major elective surgery. The goal is to improve surgical recovery and long-term health. About 440 adults scheduled for non-cancer surgery are taking part. Researchers will track how much alcohol par…

This study looked at whether a brief conversation about alcohol use can help injured patients drink less and avoid future injuries. About 830 adults admitted to the hospital for injuries took part. The goal was to see if this simple talk reduces hospital readmissions, DUIs, and r…

This study tests whether online mindfulness classes help people with alcohol use disorder stay in recovery longer than online support groups. About 470 adults who want to cut back or stop drinking will take part. The goal is to see if mindfulness training improves well-being and …

This study tests a program called Journey of Transformation for Native youth at boarding schools. It aims to delay or reduce tobacco, alcohol, and drug use and improve sexual health. About 182 tenth-grade students will take part, and researchers will compare those in the program …

This study tests a mobile program for young adults (ages 18-25) who drink heavily and have experienced trauma. It compares a standard brief intervention to one that adds coping strategies for trauma and support from peer coaches. The goal is to see if the enhanced program reduces…

This study tests a telephone-based, computer-aided care program for adults with depression, anxiety, or risky drinking. Participants receive extra support from a Mental Health Technician who helps their primary care provider manage treatment. The goal is to see if this approach r…

This study looks at how being in ketosis (a state where your body burns fat for fuel) changes the way alcohol affects your brain and body. Healthy adults will follow three different 3-day diets and then drink about 4-5 alcoholic beverages. Researchers will use breath tests and br…

This study looks at whether taking a ketone supplement before drinking alcohol changes how drunk people feel or how alcohol shows up in their breath or blood. Ten healthy volunteers will drink alcohol on two separate days, once with the supplement and once with a placebo. The goa…

This study aimed to see if a mobile app with added trauma-coping strategies and peer coaching could help young adults (ages 18-29) who drink heavily and have experienced interpersonal trauma reduce their alcohol use. Participants would have been randomly assigned to the enhanced …

This study looks at how a single dose of a ketone ester supplement changes glucose use in the brain and heart of people with and without alcohol use disorder. Twenty adults (10 with AUD, 10 healthy) will receive either the supplement or a placebo, then have a PET/CT scan. The goa…

This study planned to test a digital health worker named PAHOLA that would deliver counseling to people who drink too much alcohol but face barriers to getting treatment. The goal was to see if talking to a computer-based helper could reduce drinking and improve health. However, …

This study looks at how alcohol changes the way our brains work together during social interactions. Researchers will monitor brain activity in pairs of people while they drink alcohol. The goal is to understand the brain mechanisms behind alcohol's rewarding effects in social se…

This study is developing a program called mSTARS for people who are hospitalized after a suicide crisis and also drink heavily. The program combines in-hospital therapy with a smartphone app to help manage emotions after discharge. Ten participants will try the program and give f…