Magnetic pulses to the brain could curb alcohol cravings

NCT ID NCT04998916

Recruiting now Disease control Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a type of brain stimulation called theta burst stimulation (TBS) can reduce heavy drinking and cravings in people with alcohol use disorder. Researchers will apply magnetic pulses to a brain region linked to drinking patterns, comparing real stimulation to a sham (fake) version. The trial involves 86 adults aged 21-65 who drink heavily, and will track changes in drinking days and brain responses to alcohol cues over several months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: theta burst stimulation (TBS) using a transcranial magnetic stimulation device
What this could lead to: If it works, this could offer a non-invasive, drug-free option to help people with alcohol use disorder drink less and have more sober days.
What could go wrong: This is an early-stage study with only 86 participants, so results may not apply to everyone. The treatment is temporary and may not produce lasting changes in drinking behavior.

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Conditions

The condition(s) this trial relates to.

alcohol abuse Alcohol Drinking substance abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL DRINKING ALCOHOL USE DISORDER ALCOHOL USE DISORDER (AUD) DRINKING, ALCOHOL SUBSTANCE USE

Contacts and locations

Locations

Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29401, United States

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