AGE-RELATED MACULAR DEGENERATION

This study is testing if a high dose of a common cholesterol-lowering drug (atorvastatin) can slow the progression of intermediate age-related macular degeneration (AMD), a leading cause of vision loss. Researchers will give the drug to 21 participants and use a special 'dark ada…

This is an early-stage study to check the safety of a new treatment called ASP7317 for people with advanced dry age-related macular degeneration (AMD), a condition that causes central vision loss. The treatment involves injecting lab-grown retinal cells under the damaged part of …

This early-stage study is testing whether a single injection called VOY-101 can slow the progression of advanced dry age-related macular degeneration (AMD), a condition that causes gradual central vision loss. Researchers will give increasing doses to 60 participants aged 60+ to …

This study is testing whether a gentle electrical current applied near the eye can help slow vision loss from dry age-related macular degeneration (AMD). About 100 participants with intermediate to advanced dry AMD will use the device at home for 11 months, with some receiving a …

This study is testing a new eye injection called ABBV-6628 for people with geographic atrophy, an advanced form of dry age-related macular degeneration that causes vision loss. The main goals are to check the safety of the injection and see how the body processes it. Researchers …

This is an early-stage study to test the safety and tolerability of a new experimental drug, RO7669330, given as an injection into the eye. It is for people with geographic atrophy, an advanced form of age-related macular degeneration that leads to permanent vision loss. The main…

This study is checking the safety and side effects of a monthly eye injection called ASP3021 for people in Japan with geographic atrophy, a late-stage form of age-related macular degeneration (AMD) that causes progressive vision loss. About 20 participants will receive the inject…

This study is testing a personalized treatment schedule for a drug called faricimab, which is injected into the eye. It aims to control a serious eye disease called polypoidal choroidal vasculopathy (PCV), which can cause vision loss. The main goal is to see if patients can safel…

This study is observing how well a biosimilar version of an existing eye injection works for people with wet age-related macular degeneration (AMD), a leading cause of vision loss. It will follow 54 patients aged 45-90 who are already scheduled to receive this type of injection a…

This study is testing whether taking krill oil supplements for three months can help control dry age-related macular degeneration (AMD), a common cause of vision loss in older adults. Researchers will compare krill oil to a placebo in 24 participants with early or intermediate dr…

This study is testing whether disulfiram, a medication used to treat alcohol use disorder, can improve vision in people with retinal degeneration diseases like macular degeneration and retinitis pigmentosa. The trial will enroll 15 adults who have both a retinal condition and alc…

This study is testing a new type of eye exam that uses specially structured 'quantum' light to see if it can detect age-related macular degeneration (AMD) earlier than current methods. Researchers will test the exam on 50 people, including those with AMD, glaucoma, and healthy vi…

This study is testing whether taking a daily supplement containing lutein, zeaxanthin, and fish oil for six months can improve thinking skills and bone strength in healthy adults. Researchers will compare results between 80 participants taking the real supplement and others takin…

This study is testing a small telescope-like device that is implanted inside the eye during cataract surgery. It is designed to improve central vision for people who have lost it due to the most advanced stage of age-related macular degeneration (AMD). About 76 participants will …

This study is testing whether a one-hour educational session with an occupational therapist can help people with age-related macular degeneration, glaucoma, or diabetic retinopathy manage their medications more safely and independently. The therapist teaches practical strategies …

This study aims to understand why standard eye injections for wet age-related macular degeneration (AMD) don't work well for 20-40% of patients. Researchers will collect fluid from inside the eyes of 117 treatment-naive patients to compare those who respond well to treatment with…

This study aims to collect detailed pictures of the eyes from 1000 people, both with and without age-related macular degeneration (AMD). The goal is to create a diverse, high-quality image library that researchers can use to develop and test artificial intelligence (AI) screening…

This study aims to better understand how early-stage age-related macular degeneration (AMD) progresses toward vision loss. Researchers will follow 125 adults with early AMD using advanced eye scans and vision tests over time. The goal is to identify which patients are at highest …

This study aims to define a new concept called 'visual frailty' and create a tool to measure it. Researchers will gather information from 20 Scottish adults aged 60+ with advanced age-related macular degeneration (AMD). They will look at vision, reading ability, daily function, m…

This study is creating a research database by collecting health information and physical samples from people with and without eye diseases. Researchers will follow 650 participants over time, including those with conditions like macular degeneration and diabetic retinopathy, as w…