Can mobile eye scans in villages prevent blindness in older adults?

NCT ID NCT03752840

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This trial tests whether a community-based screening program using advanced eye imaging (OCT, fundus photography, and pressure checks) can prevent vision loss from age-related macular degeneration, diabetic retinopathy, and glaucoma better than simple vision tests alone. About 60,000 adults aged 60 and older in Nepal will be screened, and their vision will be compared nine years later. The goal is to see if early detection and referral to eye hospitals can reduce avoidable blindness at the population level.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could show that widespread community screening with advanced imaging prevents vision loss and blindness in older adults.
What could go wrong
This is a large trial, but screening programs may not improve vision at the population level, and results may not apply outside rural Nepal.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94158, United States

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Other studies related to the condition(s) this trial covers.