DIABETIC RETINOPATHY

This study is testing whether levosulpiride, a medication that increases prolactin hormone levels, can improve vision and reduce retinal damage in people with diabetic retinopathy and macular edema. Researchers will compare the drug against a placebo in 120 participants aged 40-6…

This study is testing whether performing a procedure to open blocked leg arteries within 48 hours helps diabetic foot ulcers heal better than waiting for a standard scheduled procedure. It will involve 200 adults with type 2 diabetes and a foot ulcer. Researchers will use a 3D ca…

This study is testing a new medicine called BI 764524, given as an injection into the eye, to see if it can improve or control moderate-to-severe diabetic retinopathy. Over 72 weeks, researchers will compare different dosing schedules of the new drug against sham (fake) injection…

This early-stage study is testing the safety and initial effects of a new oral medication called MS-553 for diabetic macular edema, a condition where fluid leaks into the eye, harming vision. It will enroll 45 adults with diabetes who have this specific eye swelling and have not …

This study is testing whether daily omega-3 fatty acid supplements can help maintain healthy blood vessels in the eyes of people with type 1 diabetes. Researchers will enroll 80 adults with type 1 diabetes who will take omega-3 supplements for one year while having regular eye ex…

This early-stage study is exploring whether stem cells created from a patient's own blood can repair damaged blood vessels in the eyes of people with diabetic retinopathy. Researchers will grow special 'repair cells' in the lab and test them in animal eyes first. The goal is to d…

This study is testing whether a drug that activates a protein called LXR can help prevent or slow diabetic retinopathy, a common eye complication of diabetes. Researchers believe the drug works by improving how the body handles cholesterol and reducing harmful inflammation in the…

This study compares two common laser treatment schedules for a serious diabetic eye complication that can cause blindness. Researchers want to see if getting all the laser treatment in one session is as safe and effective as spreading it over several visits. They're enrolling 40 …

This study is testing whether using artificial intelligence (AI) to screen for diabetic eye disease can help patients get treatment faster. It will compare AI analysis of eye photos to analysis by eye doctors. The goal is to see if AI can accurately identify patients who need to …

This study is testing a new AI software tool designed to spot early signs of diabetic retinopathy, a serious eye disease that can lead to blindness. The software analyzes simple retinal photos taken in a doctor's office to see if it can identify the disease as accurately as exper…

This study is testing a new 3D imaging system that gives eye surgeons a live, detailed view inside the eye during surgery. The goal is to see if this technology helps surgeons perform delicate procedures more precisely and safely. The study is enrolling patients undergoing variou…

This early study is testing a new dye called MB-102 for eye scans. The goal is to see if it is safe and works as well as the current standard dye for taking pictures of blood vessels in the back of the eye. The pictures help doctors diagnose and monitor diseases like diabetic ret…

This study is testing whether a pill called fenofibrate can prevent mild to moderate diabetic retinopathy from getting worse over 6 years. It will enroll 560 adults with diabetes and early-stage eye disease but no current swelling. The goal is to see if this widely available oral…

This study aims to understand how diabetic eye disease (retinopathy) gets worse over time. Researchers will use advanced, non-invasive eye scans to closely monitor 100 patients with moderate to severe diabetic retinopathy for two years. The goal is to identify early warning signs…

This study aims to learn if detailed pictures of the back of the eye (the retina) can help doctors predict which people with type 2 diabetes are more likely to have their diabetic eye disease get worse. It also wants to see if these same eye pictures can help predict a person's r…

This study aims to improve how doctors track eye diseases by using advanced, non-invasive imaging scans. Researchers will follow 1,050 people, including healthy volunteers and those with conditions like diabetic retinopathy, to see how blood vessels in the eye change over time. T…

This study is creating a research database by collecting health information and physical samples from people with and without eye diseases. Researchers will follow 650 participants over time, including those with conditions like macular degeneration and diabetic retinopathy, as w…