DIABETIC RETINOPATHY

This study tested an eye injection called tarcocimab in 255 people with diabetic retinopathy, a diabetes-related eye disease that can lead to vision loss. The goal was to see if the drug improves the condition better than a sham (fake) treatment. Participants received injections …

This study tested a supplement called Nuvastatic in 100 adults with type 2 diabetes who have early-stage diabetic retinopathy (non-proliferative) without swelling in the center of the retina. The goal was to see if it could reduce retinal thickness, improve vision, and lower infl…

This study tested a small, refillable implant placed in the eye that continuously releases the drug ranibizumab to treat diabetic retinopathy. 174 adults with moderate to severe non-proliferative diabetic retinopathy took part. The goal was to see if the implant could improve the…

This study tested an eye drop called INV-102 in 19 adults with diabetic macular edema, a condition where fluid builds up in the retina and can blur vision. The goal was to see if the drops could reduce retinal swelling and improve eye health over 8 to 12 weeks. The treatment is n…

This completed study looked at whether daily omega-3 fatty acid supplements can help keep the small blood vessels in the eyes healthy in adults with type 1 diabetes. 82 participants took omega-3 supplements and had regular eye exams to measure changes in their retinal blood vesse…

This study tested whether taking omega-3 supplements for 6 months could improve blood flow in the retina of people with mild to moderate diabetic retinopathy. 60 adults with diabetes and early eye damage were included. The main goal was to measure changes in tiny blood vessels in…

This study tested whether aflibercept, a medication injected into the eye, can improve areas of poor blood flow in the retina of people with diabetic retinopathy. The trial involved 38 adults with nonproliferative diabetic retinopathy and moderate retinal nonperfusion. The main g…

This study tested whether levodopa, a drug used for Parkinson's disease, can improve electrical signals in the retina of people with diabetes who have early signs of eye damage. 230 adults with diabetes took part to find the best dose and understand how the drug works. The goal i…

This study tested a new automated screening tool called OPTDR01 designed to detect diabetic retinopathy, an eye disease that can cause vision loss. The goal was to see if the tool could be easily used in primary care settings to help more people get screened, especially those who…

This study tested whether an artificial intelligence (AI) system can accurately detect diabetic eye disease and glaucoma from eye photos taken in primary care. About 900 adults with diabetes had their eye images read by both the AI and family doctors, with results compared to spe…

This study tested a nursing program designed to help people with diabetic eye disease feel less pain and stress during laser eye surgery. 136 adults were split into two groups: one received standard care, the other also got guided slow breathing, clear communication, and reassura…

This study explored whether detailed eye scans can help predict which treatment will work best for people with diabetic macular edema, a common cause of vision loss in diabetes. Researchers analyzed images from 32 participants to see if specific scan features could forecast treat…

This study tested a new device called CRYSTALSIGHT that uses artificial intelligence to track eye movements and help monitor maculopathy (a group of eye diseases that can cause vision loss). Twenty participants used the system at home to see if it works as well as existing commer…

This study compared four approaches to finding eye diseases like cataracts, glaucoma, and diabetic retinopathy in communities in Nepal. Over 87,000 people aged 50 and older took part. The goal was to see which method—comprehensive screening, cataract camps, community health worke…

This study looked at whether three substances in the blood (endocan, alarin, and galanin-like peptide) are linked to the severity of diabetic retinopathy, an eye complication of diabetes. Researchers measured these markers in 90 adults with and without diabetes and compared them …

This study looked at whether remote eye exams (tele-expertise) work as well as standard in-person visits for monitoring moderate diabetic retinopathy, a common eye problem in people with diabetes. 97 patients took part. The goal was to see if tele-expertise could correctly classi…

This study looked at 60 adults with type 2 diabetes and early-stage diabetic eye disease. Researchers used a special eye scan to measure blood flow and see if it could predict worsening vision. The goal was to find better ways to track the disease, not to test a treatment.

This study aimed to develop an artificial intelligence (AI) system to help eye doctors better predict how diabetic retinopathy (an eye disease caused by diabetes) will progress in a patient. Researchers recruited over 3,000 diabetic patients and used advanced eye imaging and AI t…

This study tested a patient navigator program for 35 adults with diabetes who had not had an eye exam in the past year and were at high risk for diabetic retinopathy, a leading cause of blindness. The goal was to see if the program was practical and acceptable, and to measure how…