New eye drug could save sight for millions with diabetes

NCT ID NCT06270836

Completed Disease control Sponsor: Kodiak Sciences Inc Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an eye injection called tarcocimab in 255 people with diabetic retinopathy, a diabetes complication that can damage vision. Participants received either the drug or a sham (fake) injection. The goal was to see if the drug improves the severity of the disease and prevents sight-threatening complications. The trial is complete, but results are not yet available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tarcocimab tedromer (injected into the eye)
What this could lead to: If it works, this could offer a new way to slow or stop vision loss from diabetic retinopathy, reducing the need for more invasive treatments.
What could go wrong: This is a completed Phase 3 trial, but results are not yet public. The drug is injected directly into the eye, which carries risks like infection or inflammation. It may not work better than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

diabetic retinopathy eye disorder retinal degeneration retinal disorder vision disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC RETINOPATHY

Contacts and locations

Locations

Asheville Eye Associates

Asheville, North Carolina, 28803, United States
Associated Vitreoretinal and Uveitis Consultants

Carmel, Indiana, 46290, United States
Austin Research Center for Retina

Austin, Texas, 78705, United States
Austin Retina Associates, PLLC (Austin)

Austin, Texas, 78705-1169, United States
Austin Retina Associates, PLLC (Round Rock)

Round Rock, Texas, 78681, United States
Cascade Medical Research Institute

Springfield, Oregon, 97477, United States
Center for Retina and Macular Disease

Winter Haven, Florida, 33880, United States
Charles Retina Institute

Germantown, Tennessee, 38138, United States
Charleston Neuroscience Institute

Charleston, South Carolina, 29414, United States
Cumberland Valley Retina Consultants

Hagerstown, Maryland, 21740, United States
Emanuelli Research & Development Center, LLC

Arecibo, 00612, Puerto Rico
Envision Ocular, LLC

Bloomfield, New Jersey, 07003, United States
Erie Retina Research

Erie, Pennsylvania, 16507, United States
Florida Eye Associates

Melbourne, Florida, 32901, United States
Global Research Management, Inc. - Lugene Eye Institute

Glendale, California, 91204, United States
North Carolina Retina Associates (Cary)

Cary, North Carolina, 27511, United States
North Carolina Retina Associates (Wake Forest)

Wake Forest, North Carolina, 27587, United States
Pacific Northwest Retina (Bellevue)

Bellevue, Washington, 98004, United States
Panhandle Eye Group, LLP. - Southwest Retina Specialists

Amarillo, Texas, 79106, United States
Piedmont Eye Center

Lynchburg, Virginia, 24502, United States
Retina Associates SW

Tucson, Arizona, 85704, United States
Retina Consultants of Nevada

Henderson, Nevada, 89052, United States
Retina Consultants of Orange County

Fullerton, California, 92835, United States
Retina Consultants of Southern California

Redlands, California, 92374, United States
Retina Consultants of Texas (Bellaire)

Bellaire, Texas, 77401, United States
Retina Consultants of Texas (Katy)

Katy, Texas, 77494, United States
Retina Consultants of Texas (San Antonio)

San Antonio, Texas, 78240, United States
Retina Consultants of Texas (Woodlands)

The Woodlands, Texas, 77384, United States
Retina Group of Florida

Fort Lauderdale, Florida, 33308, United States
Retina Group of New England, PC

Waterford, Connecticut, 06385, United States
Retina Research Institute of Texas

Abilene, Texas, 79606, United States
Retinal Consultants Medical Group, Inc.

Modesto, California, 95356, United States
Retinal Consultants Medical Group, Inc.

Sacramento, California, 95825, United States
Southeast Retina Center

Augusta, Georgia, 30909, United States
Southeastern Retina Associates PC

Knoxville, Tennessee, 37922, United States
Spokane Eye Clinical Research

Spokane, Washington, 99204, United States
Springfield Clinic LLP

Springfield, Illinois, 62703, United States
Star Vision Research

Burleson, Texas, 76028, United States
Texas Retina Associates

Plano, Texas, 75075, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.