New eye drug could save sight for millions with diabetes

NCT ID NCT06270836

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an eye injection called tarcocimab in 255 people with diabetic retinopathy, a diabetes complication that can damage vision. Participants received either the drug or a sham (fake) injection. The goal was to see if the drug improves the severity of the disease and prevents sight-threatening complications. The trial is complete, but results are not yet available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tarcocimab tedromer (injected into the eye)

What this could lead to

If it works, this could offer a new way to slow or stop vision loss from diabetic retinopathy, reducing the need for more invasive treatments.

What could go wrong

This is a completed Phase 3 trial, but results are not yet public. The drug is injected directly into the eye, which carries risks like infection or inflammation. It may not work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetic retinopathy eye disorder retinal degeneration retinal disorder vision disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asheville Eye Associates

    Asheville, North Carolina, 28803, United States

  • Associated Vitreoretinal and Uveitis Consultants

    Carmel, Indiana, 46290, United States

  • Austin Research Center for Retina

    Austin, Texas, 78705, United States

  • Austin Retina Associates, PLLC (Austin)

    Austin, Texas, 78705-1169, United States

  • Austin Retina Associates, PLLC (Round Rock)

    Round Rock, Texas, 78681, United States

  • Cascade Medical Research Institute

    Springfield, Oregon, 97477, United States

  • Center for Retina and Macular Disease

    Winter Haven, Florida, 33880, United States

  • Charles Retina Institute

    Germantown, Tennessee, 38138, United States

  • Charleston Neuroscience Institute

    Charleston, South Carolina, 29414, United States

  • Cumberland Valley Retina Consultants

    Hagerstown, Maryland, 21740, United States

  • Emanuelli Research & Development Center, LLC

    Arecibo, 00612, Puerto Rico

  • Envision Ocular, LLC

    Bloomfield, New Jersey, 07003, United States

  • Erie Retina Research

    Erie, Pennsylvania, 16507, United States

  • Florida Eye Associates

    Melbourne, Florida, 32901, United States

  • Global Research Management, Inc. - Lugene Eye Institute

    Glendale, California, 91204, United States

  • North Carolina Retina Associates (Cary)

    Cary, North Carolina, 27511, United States

  • North Carolina Retina Associates (Wake Forest)

    Wake Forest, North Carolina, 27587, United States

  • Pacific Northwest Retina (Bellevue)

    Bellevue, Washington, 98004, United States

  • Panhandle Eye Group, LLP. - Southwest Retina Specialists

    Amarillo, Texas, 79106, United States

  • Piedmont Eye Center

    Lynchburg, Virginia, 24502, United States

  • Retina Associates SW

    Tucson, Arizona, 85704, United States

  • Retina Consultants of Nevada

    Henderson, Nevada, 89052, United States

  • Retina Consultants of Orange County

    Fullerton, California, 92835, United States

  • Retina Consultants of Southern California

    Redlands, California, 92374, United States

  • Retina Consultants of Texas (Bellaire)

    Bellaire, Texas, 77401, United States

  • Retina Consultants of Texas (Katy)

    Katy, Texas, 77494, United States

  • Retina Consultants of Texas (San Antonio)

    San Antonio, Texas, 78240, United States

  • Retina Consultants of Texas (Woodlands)

    The Woodlands, Texas, 77384, United States

  • Retina Group of Florida

    Fort Lauderdale, Florida, 33308, United States

  • Retina Group of New England, PC

    Waterford, Connecticut, 06385, United States

  • Retina Research Institute of Texas

    Abilene, Texas, 79606, United States

  • Retinal Consultants Medical Group, Inc.

    Modesto, California, 95356, United States

  • Retinal Consultants Medical Group, Inc.

    Sacramento, California, 95825, United States

  • Southeast Retina Center

    Augusta, Georgia, 30909, United States

  • Southeastern Retina Associates PC

    Knoxville, Tennessee, 37922, United States

  • Spokane Eye Clinical Research

    Spokane, Washington, 99204, United States

  • Springfield Clinic LLP

    Springfield, Illinois, 62703, United States

  • Star Vision Research

    Burleson, Texas, 76028, United States

  • Texas Retina Associates

    Plano, Texas, 75075, United States