DIABETIC RETINOPATHY

This study tests whether a daily pill called fenofibrate can slow or prevent worsening eye disease (diabetic retinopathy) in adults with type 1 diabetes. About 412 participants with early eye damage are taking either the drug or a placebo for several years. The goal is to see if …

This study tests whether levodopa, a drug used for Parkinson's, can slow the early blood vessel changes in the eyes of people with diabetes. About 244 adults with diabetes and early signs of retinal problems will take the drug. The goal is to see if it delays worsening of diabeti…

This study tests a gene therapy called 4D-150 for people with diabetic macular edema, a condition where fluid builds up in the eye and blurs vision. About 72 adults who still need regular eye injections will receive either the gene therapy or standard treatment. The goal is to se…

This study tests a new medicine called BI 764524 in 187 adults with moderate to severe diabetic retinopathy, a diabetes complication that can damage eyesight. Participants receive different numbers of eye injections over a year, and doctors compare their eye health to those getti…

This early-stage study tests whether it is safe to take a person's own bone marrow stem cells and inject them into the eye to treat blindness caused by diseases like macular degeneration and diabetic retinopathy. Fifteen adults with severe vision loss will receive the injection a…

This study is gathering information on eye blood vessels from healthy children aged 6-15 to create a standard reference. Researchers will then compare this data to children with type 1 diabetes to spot early signs of diabetic retinopathy. The goal is to better understand and even…

This study looks at blood stem cells (called EPCs) in people with diabetes and healthy volunteers to understand why they may not work properly in diabetes. Researchers want to see if these cells can predict the development of diabetic retinopathy, an eye disease that can cause bl…

This study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early. Participants get two screenings a year apart to track t…

This study tests a program called I-SITE, which uses teleophthalmology (taking eye photos remotely) to increase diabetic eye screening rates in urban health systems. Over 12,000 people with diabetes are included. The goal is to see if this approach helps more patients get regular…

This study looks at whether a special type of eye scan (functional OCT) can detect early blood vessel damage in people with diabetic retinopathy without needing a dye injection. Researchers will compare the new scan to the standard dye-based test in 165 adults with diabetes. The …

This study tests a new type of eye scan (OCTA) that doesn't require dye injections to see blood vessels in the back of the eye. Researchers want to see if it can measure damage from diabetic retinopathy as well as or better than current methods. About 290 people with diabetes wil…

This study is creating a large biobank of health information and blood samples from 48,000 people with diabetes in Hong Kong. Researchers will analyze genes and other markers to better predict who is at risk for serious complications like kidney failure, heart disease, and stroke…

This study looks at whether inflammation in the eye is linked to worsening diabetic retinopathy, a common diabetes complication that can lead to vision loss. Researchers are testing if ketorolac eye drops can reduce inflammation and slow the disease. About 164 adults with type 2 …

This study tests whether AI-assisted software helps eye doctors diagnose four common eye diseases more accurately and quickly. Ten eye doctors and residents will review eye images with and without AI help. The goal is to see if AI improves diagnosis and saves time.