Common heart drug may shield eyes of type 1 diabetes patients
NCT ID NCT01320345
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether fenofibrate, a drug typically used to lower blood fats, can slow the worsening of diabetic retinopathy (eye damage) in adults with type 1 diabetes. Over 400 participants take either fenofibrate or a placebo daily for three years. The goal is to see if the drug reduces the need for laser surgery or other eye treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Fenofibrate (a drug that lowers fats in the blood)
- What this could lead to
- If it works, fenofibrate could become a new way to slow or prevent vision loss from diabetic retinopathy in people with type 1 diabetes.
- What could go wrong
- This is a phase 3 trial, but results are not yet reported. Fenofibrate may not slow retinopathy enough to be useful, and it can cause side effects like muscle pain or liver issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Auckland Diabetes Centre
Auckland, 1051, New Zealand
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Baker Heart and Diabetes Institute
Melbourne, Victoria, 3004, Australia
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Belfast Health and Social Care Trust
Belfast, BT12 6BA, United Kingdom
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Cairns Hospital
Cairns, Queensland, 4870, Australia
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Canberra Hospital
Garran, Australian Capital Territory, 2605, Australia
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Christchurch Hospital
Christchurch, 8011, New Zealand
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Concord Repatriation General Hospital
Concord, New South Wales, 2139, Australia
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Fremantle Hospital
Fremantle, Western Australia, 6160, Australia
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Garvan Institute of Medical Research
Darlinghurst, New South Wales, 2010, Australia
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Heidelberg Repatriation Hospital
Heidelberg, Victoria, 3081, Australia
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Hunter Diabetes Centre
Merewether, New South Wales, 2291, Australia
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Mater Adult Hospital
South Brisbane, Queensland, 4101, Australia
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Prince of Wales Hospital
Randwick, New South Wales, 2032, Australia
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Prince of Wales Hospital
Shatin, New Territories, Hong Kong
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Princess Alexandra Hospital
Woolloongabba, Queensland, 4102, Australia
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Retina Associates - South West Retina
Liverpool, New South Wales, 2170, Australia
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Royal Adelaide Hospital
Adelaide, South Australia, 5000, Australia
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Royal North Shore Hospital
Saint Leonards, New South Wales, 2065, Australia
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Royal Prince Alfred Hospital
Camperdown, New South Wales, 2050, Australia
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Southern Adelaide Diabetes and Endocrine Services
Oaklands Park, South Australia, 5046, Australia
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St Vincent's Hospital Melbourne
Melbourne, Victoria, 3065, Australia
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Sunshine Hospital
St Albans, Victoria, 3021, Australia
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The Royal Melbourne Hospital
Parkville, Victoria, 3050, Australia
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University Hospital Geelong
Geelong, Victoria, 3220, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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