Melatonin may fix sleep in diabetic eye disease

NCT ID NCT04547439

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking 3 mg of melatonin each night for 8 weeks can improve sleep and daily body rhythms in people with diabetic retinopathy. Researchers will track sleep patterns and hormone levels in 42 adults aged 40-65 with type 2 diabetes and moderate eye damage. The goal is to see if this simple supplement can ease sleep problems linked to the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Melatonin
What this could lead to
If it works, this could point toward a simple, low-cost way to improve sleep and daily rhythms for people with diabetic retinopathy.
What could go wrong
This is a small, early-phase trial with only 42 participants. Melatonin may not improve sleep or eye health, and results may not apply to everyone with diabetes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60612, United States

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