Melatonin may fix sleep in diabetic eye disease

NCT ID NCT04547439

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking 3 mg of melatonin each night for 8 weeks can improve sleep and daily body rhythms in people with diabetic retinopathy. Researchers will track sleep patterns and hormone levels in 42 adults aged 40-65 with type 2 diabetes and moderate eye damage. The goal is to see if this simple supplement can ease sleep problems linked to the condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Melatonin

What this could lead to

If it works, this could point toward a simple, low-cost way to improve sleep and daily rhythms for people with diabetic retinopathy.

What could go wrong

This is a small, early-phase trial with only 42 participants. Melatonin may not improve sleep or eye health, and results may not apply to everyone with diabetes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus diabetic retinopathy type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact