New eye drug tiespectus takes on aflibercept in major wet AMD trial

NCT ID NCT07440225

Recruiting now Disease control Sponsor: EyeBiotech Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 4 times

Summary

This study tests a new medicine called tiespectus (EYE201) for wet age-related macular degeneration, a leading cause of vision loss. About 960 people will receive either tiespectus or the standard treatment aflibercept via eye injections. The goal is to see if tiespectus can improve or maintain eyesight as well as the current drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Associated Vitreoretinal and Uveitis Consultants
RECRUITING

Carmel, Indiana, 46032, United States

Contact Phone: •••-•••-••••
Austin Research Center for Retina
RECRUITING

Austin, Texas, 78705, United States

Contact Phone: •••-•••-••••
Austin Retina Associates (Site 012)
RECRUITING

Austin, Texas, 78705, United States

Contact Phone: •••-•••-••••
Barzilai Medical Center
RECRUITING

Ashkelon, 7830604, Israel

Contact Phone: •••-•••-••••
Carmel Medical Center (Site 704)
RECRUITING

Haifa, 3436212, Israel

Contact Phone: •••-•••-••••
Centro Oftalmologico Dr Charles y Asociados (Site 300)
RECRUITING

Buenos Aires, C1121ABB, Argentina

Contact Phone: •••-•••-••••
Centro Oftalmológico Dr. Zas
RECRUITING

Buenos Aires, PC1023, Argentina

Contact
Centro Privado de Ojos Romagosa SA (Site 307)
RECRUITING

Córdoba, X5000AAI, Argentina

Contact Phone: •••-•••-••••
Centro de Ojos Loria SRL (Site 312)
RECRUITING

Buenos Aires, CP1832, Argentina

Contact Phone: •••-•••-••••
Centro de Ojos Quilmes
RECRUITING

Buenos Aires, B1878KDF, Argentina

Contact Phone: •••-•••-••••
Centro de la Visión (Site 309)
RECRUITING

Salta, A4400, Argentina

Contact Phone: •••-•••-••••
Centrovision Clinica Oftalmologica
RECRUITING

Mendoza, 5500, Argentina

Contact Phone: •••-•••-••••
Charles Retina Institute
RECRUITING

Germantown, Tennessee, 38138, United States

Contact Phone: •••-•••-••••
Charleston Neuroscience Institute (CNI) d/b/a Retina Consultants of South Carolina
RECRUITING

Mt. Pleasant, South Carolina, 29464, United States

Contact Phone: •••-•••-••••
Charleston Neuroscience Institute (Site 104)
RECRUITING

Charleston, South Carolina, 29414, United States

Contact Phone: •••-•••-••••
Charleston Neuroscience Institute - Bluffton (Site 124)
RECRUITING

Bluffton, South Carolina, 29910, United States

Contact Phone: •••-•••-••••
Cincinnati Eye Institute (Site 133)
RECRUITING

Cincinnati, Ohio, 45242, United States

Contact Phone: •••-•••-••••
Clinica de Oftalmologia Barraquer
RECRUITING

Barcelona, 08021, Spain

Contact Phone: •••-•••-••••
Cumberland Valley Retina Consultants (Site 007)
RECRUITING

Hagerstown, Maryland, 21740, United States

Contact Phone: •••-•••-••••
Eye Clinic Albury Wodonga (Site 425)
RECRUITING

Albury, 2640 NSW, Australia

Contact Phone: •••-•••-••••
EyeHealth Northwest
RECRUITING

Portland, Oregon, 97225, United States

Contact Phone: •••-•••-••••
Florida Eye Clinic (Site 130)
RECRUITING

Altamonte Springs, Florida, 32701, United States

Contact Phone: •••-•••-••••
Fort Lauderdale Eye Institute (Site 042)
RECRUITING

Plantation, Florida, 33324, United States

Contact Phone: •••-•••-••••
Foundation for Vision Research (Site 073)
RECRUITING

Grand Rapids, Michigan, 49546, United States

Contact Phone: •••-•••-••••
Fundacion Jorge Zambrano para la investigación, diagnostivo y tratamiento de enfermedades oculares (Site 302)
RECRUITING

Buenos Aires, C1023AAQ, Argentina

Contact Phone: •••-•••-••••
Global Research Management, Inc.
RECRUITING

Glendale, California, 91204, United States

Contact Phone: •••-•••-••••
Grupo Laser Vision (Rosario Eximer Laser Vision SA)
RECRUITING

Rosario, Santa Fe Province, S2000DLA, Argentina

Contact Phone: •••-•••-••••
Hadassah Medical Center Opthalmology Department (Site 701)
RECRUITING

Jerusalem, 9112001, Israel

Contact Phone: •••-•••-••••
Illinois Retina Associates
RECRUITING

Oak Park, Illinois, 60304, United States

Contact Phone: •••-•••-••••
Instituto Donato
RECRUITING

Cdad. Autónoma de Buenos Aires, C1428, Argentina

Contact Phone: •••-•••-••••
Instituto Oftalmologico de Buenos Aires SA (Site 306)
RECRUITING

Buenos Aires, C1120AAN, Argentina

Contact Phone: •••-•••-••••
Instituto Zeman Bardeci (Site 311)
RECRUITING

Salta, A4400, Argentina

Contact Phone: •••-•••-••••
Instituto de Microcirugía Ocular Córdoba (IMOC S.R.L) (Site 305)
RECRUITING

Córdoba, 5000, Argentina

Contact Phone: •••-•••-••••
Kaplan Medical Center Ophthalmology Department (Site 705)
RECRUITING

Rehovot, 7661005, Israel

Contact Phone: •••-•••-••••
London North West University Healthcare NHS Trust (LNWH) (Site 201)
RECRUITING

London, NW10 7NS, United Kingdom

Contact Phone: •••-•••-••••
Marsden Eye Specialists (Site 420)
RECRUITING

Parramatta, 2150, NSW, Australia

Contact Phone: •••-•••-••••
Marsden Eye Specialists (Site 423)
RECRUITING

Strathfield, 2135 NSW, Australia

Contact Phone: •••-•••-••••
Microcirugia Ocular Rosario (Site 310)
RECRUITING

Rosario, Santa Fe Province, S2000TC, Argentina

Contact Phone: •••-•••-••••
Mid Atlantic Retina
RECRUITING

Cherry Hill, New Jersey, 08034, United States

Contact Phone: •••-•••-••••
Mid Atlantic Retina (Site 050)
RECRUITING

Bethlehem, Pennsylvania, 18017, United States

Contact Phone: •••-•••-••••
Mississippi Retina Associates (Site 084)
RECRUITING

Madison, Mississippi, 39110, United States

Contact Phone: •••-•••-••••
Oftalmología Global (Centro Médico Oftalmología Global) (Site 304)
RECRUITING

Rosario, Santa Fe Province, S2000DSK, Argentina

Contact Phone: •••-•••-••••
Oftar Centro De Oftalmología en Mendoza
RECRUITING

Mendoza, 5500, Argentina

Contact Phone: •••-•••-••••
P.Stradins clinical university hospital
RECRUITING

Riga, LV1002, Latvia

Contact Phone: •••-•••-••••
Pacific Northwest Retina (Site 112)
RECRUITING

Burlington, Washington, 98233, United States

Contact Phone: •••-•••-••••
Palmetto Retina Center
RECRUITING

Aiken, South Carolina, 29803, United States

Contact Phone: •••-•••-••••
Piedmont Eye Center (Site 054)
RECRUITING

Lynchburg, Virginia, 24502, United States

Contact Phone: •••-•••-••••
Piedmont Retina Specialists - Winston-Salem
RECRUITING

Winston-Salem, North Carolina, 27103, United States

Contact Phone: •••-•••-••••
RSresearch (Site 308)
RECRUITING

Buenos Aires, C1033AAW, Argentina

Contact Phone: •••-•••-••••
Rabin Medical Center (Site 700)
RECRUITING

Petah Tikva, 49100, Israel

Contact Phone: •••-•••-••••
Rambam Health Corporation (Site 706)
RECRUITING

Haifa, 3109601, Israel

Contact Phone: •••-•••-••••
Research Network Arizona / Retina Macula Institute of Arizona
RECRUITING

Scottsdale, Arizona, 85255, United States

Contact Phone: •••-•••-••••
Retina & Vitreous of Texas
RECRUITING

Bellaire, Texas, 77401, United States

Contact Phone: •••-•••-••••
Retina Associates of Florida, LLC
RECRUITING

Tampa, Florida, 33609, United States

Contact Phone: •••-•••-••••
Retina Associates of Utah
RECRUITING

Salt Lake City, Utah, 84107, United States

Contact Phone: •••-•••-••••
Retina Center of Arkansas
RECRUITING

Fayetteville, Arkansas, 72703, United States

Contact Phone: •••-•••-••••
Retina Center of Texas
RECRUITING

Southlake, Texas, 76092, United States

Contact Phone: •••-•••-••••
Retina Consultants of Southern California (Site 043)
RECRUITING

Redlands, California, 92374, United States

Contact Phone: •••-•••-••••
Retina Consultants of Texas (Site 014)
RECRUITING

The Woodlands, Texas, 77384, United States

Contact Phone: •••-•••-••••
Retina Consultants, PLLC
RECRUITING

Charleston, West Virginia, 25301, United States

Contact Phone: •••-•••-••••
Retina Group of Florida (Site 070)
RECRUITING

Fort Lauderdale, Florida, 33308, United States

Contact Phone: •••-•••-••••
Retina Northwest, PC
RECRUITING

Portland, Oregon, 97221, United States

Contact Phone: •••-•••-••••
Retina Partners of Northwest Arkansas, PLLC
RECRUITING

Springdale, Arkansas, 72764, United States

Contact Phone: •••-•••-••••
Retina Research Institute of Texas (Site 010)
RECRUITING

Abilene, Texas, 79606, United States

Contact Phone: •••-•••-••••
Retina Vitreous Associates of Florida
RECRUITING

Tampa, Florida, 33617, United States

Contact Phone: •••-•••-••••
Retina Vitreous Associates of Florida (Site 049)
RECRUITING

St. Petersburg, Florida, 33711, United States

Contact Phone: •••-•••-••••
Retina Vitreous Surgeons of CNY, PC (Site 033)
RECRUITING

Liverpool, New York, 13088, United States

Contact Phone: •••-•••-••••
Retinal Consultants Medical Group (Site 020)
RECRUITING

Sacramento, California, 95825, United States

Contact Phone: •••-•••-••••
Retinal Consultants Medical Group (Site 022)
RECRUITING

Sacramento, California, 95841, United States

Contact Phone: •••-•••-••••
Retinal Consultants Medical Group (Site 024)
RECRUITING

Modesto, California, 95356, United States

Contact Phone: •••-•••-••••
Shamir Medical Center (Site 703)
RECRUITING

Ẕerifin, 7033001, Israel

Contact Phone: •••-•••-••••
Sheba Medical Center (Site 707)
RECRUITING

Ramat Gan, 6265601, Israel

Contact Phone: •••-•••-••••
Southern Vitreoretinal Associates
RECRUITING

Tallahassee, Florida, 32308, United States

Contact Phone: •••-•••-••••
Southwest Retina Specialists
RECRUITING

Amarillo, Texas, 79106, United States

Contact Phone: •••-•••-••••
Spokane Eye Clinical Research (Site 075)
RECRUITING

Spokane, Washington, 99204, United States

Contact Phone: •••-•••-••••
Springfield Clinic
RECRUITING

Springfield, Illinois, 62703, United States

Contact Phone: •••-•••-••••
Stadtspital Zurich Triemli Forschungszentrum Augenklinik
RECRUITING

Zurich, CH-8063, Switzerland

Contact Phone: •••-•••-••••
Strategic Clinical Research Group
RECRUITING

Weatherford, Texas, 76087, United States

Contact Phone: •••-•••-••••
Swiss Eye Institute and Berner Augenklinik
RECRUITING

Bern, CH-3007, Switzerland

Contact Phone: •••-•••-••••
Sydney Eye Hospital (Site 426)
RECRUITING

Sydney, 2000 NSW, Australia

Contact Phone: •••-•••-••••
Sydney Retina Clinic and Day Surgery (Site 424)
RECRUITING

Sydney, 2000, NSW, Australia

Contact Phone: •••-•••-••••
Texas Retina (Site 037)
RECRUITING

Plano, Texas, 75075, United States

Contact Phone: •••-•••-••••
Texas Retina Associates
RECRUITING

Arlington, Texas, 76012, United States

Contact Phone: •••-•••-••••
Texas Retina Associates
RECRUITING

Dallas, Texas, 75231, United States

Contact Phone: •••-•••-••••
Tulsa Retina Consultants
RECRUITING

Tulsa, Oklahoma, 74114, United States

Contact Phone: •••-•••-••••
University Hospital Basel, Eye Clinic
RECRUITING

Basel, CH-4031, Switzerland

Contact Phone: •••-•••-••••
University Hospitals of Leicester NHS Trust (Site 209)
RECRUITING

Leicester, LE1 5WW, United Kingdom

Contact Phone: •••-•••-••••
Vista Augenklinik Binningen
RECRUITING

Binnigen, CH-4102, Switzerland

Contact Phone: •••-•••-••••
Vitreo Retinal Associates
RECRUITING

Gainesville, Florida, 32607, United States

Contact Phone: •••-•••-••••
Wildwood Clinical Research / Florida Retina Institute
RECRUITING

Wildwood, Florida, 34785, United States

Contact Phone: •••-•••-••••
ong Island Vitreoretinal Consultants / Vitreoretinal Consultants of NY (Site 105)
RECRUITING

Hauppauge, New York, 11788, United States

Contact Phone: •••-•••-••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.