MACULAR DEGENERATION

This study tests a new medicine called tiespectus (EYE201) against the standard treatment aflibercept for wet age-related macular degeneration, a leading cause of vision loss. About 960 people with untreated wet AMD will receive eye injections and be followed for one year to comp…

This study follows people who already received an eye injection of JNJ-81201887 or a sham in earlier trials for geographic atrophy, a form of advanced age-related macular degeneration. The goal is to check long-term safety by monitoring eye health and side effects over time. Abou…

This study tests a new medicine called tiespectus (EYE201) against the standard treatment aflibercept for wet age-related macular degeneration (AMD), a leading cause of vision loss. About 960 adults with untreated wet AMD will receive injections into the eye to see if tiespectus …

This early study tests a new dye called MB-102 for taking pictures of the blood vessels in the back of the eye. The goal is to see if it is safe and provides good images compared to the standard dye used today. About 10 adults with healthy eyes or conditions like diabetic retinop…

This study tests whether a gentle brain stimulation technique (a-tDCS) combined with reading training can help people with age-related or juvenile macular degeneration read words on a screen better than training alone. About 30 adults with stable central vision loss will do six t…

This study tests whether a 5-week eye training program using visual and sound feedback can help people with central vision loss (from macular degeneration) use their peripheral vision more effectively. About 12 participants will do eye-tracking exercises while getting real-time c…

This study looks at how people with severe vision loss from macular degeneration can train their brains to use their remaining side vision more effectively. Researchers will measure changes in eye movements and focus after about 7 weeks of training. The goal is to understand brai…

This study looks at how color vision loss progresses in people with inherited retinal diseases (IRDs) and how it relates to changes in the retina's structure. About 200 participants, including those with various IRDs and healthy controls, will take color vision tests and have det…

This study follows 1,000 people with geographic atrophy (an advanced form of age-related macular degeneration) who are already starting treatment with the drug Izervay. Researchers will collect information from medical records and surveys over up to 5 years to see how the drug is…