New eye drug IZERVAY under Real-World watch: will it slow vision loss?

NCT ID NCT06779773

Recruiting now Knowledge-focused Sponsor: Astellas Pharma Global Development, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 500 people with geographic atrophy, an advanced form of age-related macular degeneration that causes permanent vision loss. Participants receive avacincaptad pegol (IZERVAY) as part of their routine care. Researchers will collect data on treatment patterns, side effects, and patient-reported outcomes over up to 5 years to see how the drug performs in real-world settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

avacincaptad pegol (IZERVAY)

What this could lead to

If successful, this study could provide valuable information on how avacincaptad pegol works in everyday medical practice, helping doctors better manage geographic atrophy.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may be influenced by differences in patient care and may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

age-related macular degeneration dry age related macular degeneration Geographic Atrophy macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GEOGRAPHIC ATROPHY MACULAR DEGENERATION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Advanced Retina Institute
RECRUITING

Bonita Springs, Florida, 34134, United States
Brown Family Retina PLLC
RECRUITING

Olive Branch, Mississippi, 38654, United States
CEI Physicians PSC, LLC dba
RECRUITING

Dayton, Ohio, 45459, United States
Coastal Eye Surgeons
RECRUITING

Greenwich, Connecticut, 05830, United States
Colorado Retina Associates, PLLC
RECRUITING

Lakewood, Colorado, 80228, United States
Cumberland Valley Retina Consultants,P.C.
RECRUITING

Hagerstown, Maryland, 21740, United States
Deep Blue Retina Clinical Research
RECRUITING

Southaven, Mississippi, 38671, United States
Erie Retina Research
RECRUITING

Erie, Pennsylvania, 16507, United States
Eye Associates of North Jersey PA
RECRUITING

Dover, New Jersey, 07801, United States
Eye Physicians of Pinellas PA dba Eye Institute of West Florida
RECRUITING

Tampa, Florida, 33606, United States
Florida Eye Clinic
WITHDRAWN

Altamonte Springs, Florida, 32701, United States
Harvard Eye Associates
RECRUITING

Laguna Hills, California, 92653, United States
Illinois Eye Center
RECRUITING

Peoria, Illinois, 61615, United States
Illinois Retina Associates
RECRUITING

Oak Park, Illinois, 60304, United States
Long Island Vitreoretinal Consultants
RECRUITING

Scarsdale, New York, 10583, United States
Medical Center Ophthalmology Associates
RECRUITING

San Antonio, Texas, 78240, United States
Mid South Retina Associates
RECRUITING

Memphis, Tennessee, 38119, United States
Mississippi Retina Associates
RECRUITING

Madison, Mississippi, 39110, United States
Monmouth Retina Consultants
WITHDRAWN

Little Silver, New Jersey, 07739, United States
NJ Retina
RECRUITING

Edison, New Jersey, 08820, United States
NJ Retina
RECRUITING

Lakewood, New Jersey, 08701, United States
NJ Retina
RECRUITING

Toms River, New Jersey, 08755, United States
NY Retina Ophthalmology PLLC
ACTIVE_NOT_RECRUITING

Massapequa, New York, 11758, United States
North Carolina Retina Associates
WITHDRAWN

Cary, North Carolina, 27511, United States
North Carolina Retina Associates
RECRUITING

Wake Forest, North Carolina, 27587, United States
Phoenix Retina Clinical Trials, LLC
RECRUITING

Phoenix, Arizona, 85050, United States
Piedmont Eye Center, Inc.
RECRUITING

Lynchburg, Virginia, 24502, United States
Retina & Vitreous Consultants of Wisconsin
ACTIVE_NOT_RECRUITING

Milwaukee, Wisconsin, 53226, United States
Retina & Vitreous of Texas
WITHDRAWN

Bellaire, Texas, 77401, United States
Retina Associates Of South Texas, Pa
RECRUITING

San Antonio, Texas, 78240, United States
Retina Associates of Michigan
RECRUITING

Grand Blanc, Michigan, 48439, United States
Retina Associates of New York
ACTIVE_NOT_RECRUITING

New York, New York, 10075, United States
Retina Associates of Utah, P.C.
RECRUITING

Murray, Utah, 84107, United States
Retina Care Specialists
RECRUITING

Palm Beach Gardens, Florida, 33410, United States
Retina Consultants of Minnesota PLLC
RECRUITING

Saint Louis Park, Minnesota, 55416, United States
Retina Consultants of Southern CA
RECRUITING

Redlands, California, 92374, United States
Retina Consultants of Southern Colorado
RECRUITING

Colorado Springs, Colorado, 80909, United States
Retina Macula Institute
RECRUITING

Torrance, California, 90503, United States
Retina Macula Institute of Arizona
RECRUITING

Scottsdale, Arizona, 85255, United States
Retina Research Institute of Texas
RECRUITING

Abilene, Texas, 79606, United States
Retina Specialists
WITHDRAWN

Towson, Maryland, 21204, United States
Retina Specialists of Tampa
RECRUITING

Wesley Chapel, Florida, 33544, United States
Retina of North Texas
RECRUITING

Dallas, Texas, 75243, United States
Retina-Vitreous Surgeons of Central NY
RECRUITING

Liverpool, New York, 13088, United States
Retinal Consultants Medical Group Inc
RECRUITING

Sacramento, California, 95825, United States
Retinal Consultants of AZ
RECRUITING

Phoenix, Arizona, 85053, United States
Rocky Mountain Lions Eye Institute
RECRUITING

Aurora, Colorado, 80045, United States
Salt Lake Retina
RECRUITING

Salt Lake City, Utah, 84120, United States
Sierra Eye Associates
ACTIVE_NOT_RECRUITING

Reno, Nevada, 89502, United States
SightMD
RECRUITING

Brentwood, New York, 11717, United States
Southeast Retina Center, P.C.
RECRUITING

Augusta, Georgia, 30909, United States
Southeastern Retina Associates, P.C.
RECRUITING

Knoxville, Tennessee, 37920, United States
Southeastern Retina Associates, P.C.
RECRUITING

Knoxville, Tennessee, 37923, United States
Tennessee Retina, PC
RECRUITING

Nashville, Tennessee, 37203, United States
The Ohio State University
RECRUITING

Columbus, Ohio, 43221, United States
The Retina Group of Washington
RECRUITING

Fairfax, Virginia, 22031, United States
The Retina Partners
WITHDRAWN

Encino, California, 91436, United States
University Retina and Macula Associates, P.C.
RECRUITING

Oak Forest, Illinois, 60452, United States
University of California Irvine Medical Center
RECRUITING

Orange, California, 92868, United States
University of Miami
RECRUITING

Coral Gables, Florida, 33146, United States
Valley Retina Institute
RECRUITING

McAllen, Texas, 78503, United States
Verum Research, LLC
RECRUITING

Eugene, Oregon, 97401, United States
Virginia Retina Center
RECRUITING

Warrenton, Virginia, 20186, United States
Vitreoretinal Consultants
RECRUITING

Shirley, New York, 11967, United States
Wolfe Eye Clinic
RECRUITING

West Des Moines, Iowa, 50266, United States