New eye drug aims to outperform standard treatment for blinding disease

NCT ID NCT07496567

First seen Apr 14, 2026 · Last updated May 15, 2026 · Updated 5 times

Summary

This study tests a new medicine called tiespectus (EYE201/MK-8748) against the standard treatment aflibercept for wet age-related macular degeneration, a leading cause of vision loss. About 960 adults with untreated wet AMD will receive injections into the eye to see if the new drug works as well or better at preserving eyesight. The trial is currently recruiting participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Charleston Neuroscience Institute

    RECRUITING

    Ladson, South Carolina, 29456, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Envision Ocular, LLC

    RECRUITING

    Bloomfield, New Jersey, 07003, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Erie Retina Research

    RECRUITING

    Erie, Pennsylvania, 16505, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mid Atlantic Retina Specialists

    RECRUITING

    Hagerstown, Maryland, 21740, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northern California Retina Vitreous Associates Medical Group, Inc.

    RECRUITING

    Mountain View, California, 94040, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Pacific Northwest Retina

    RECRUITING

    Bellevue, Washington, 98004, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Retina Consultants of Minnesota

    RECRUITING

    Edina, Minnesota, 55435, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Retina Consultants of Texas

    RECRUITING

    Bellaire, Texas, 77401, United States

    Contact

    Contact Email: •••••@•••••

  • University Retina & Macula Associates, P.C.

    RECRUITING

    Lemont, Illinois, 60439, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.