Choroidal neovascularization
MONDO:0810000An eye disorder described by the growth of new blood vessels that originate from the choroid through a break in the Bruch membrane into the sub–retinal pigment epithelium (sub-RPE) or subretinal space. Choroidal neovascularization (CNV) is a major cause of visual loss.
21 clinical trials for this condition and its sub-types.
Follow this condition to get notified about new trialsBroader categories
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New eye drug tiespectus takes on aflibercept in major wet AMD trial
Disease control Recruiting nowThis study tests a new medicine called tiespectus (EYE201) for wet age-related macular degeneration, a leading cause of vision loss. About 960 people will receive either tiespectus or the standard treatment aflibercept via eye injections. The goal is to see if tiespectus can impr…
Phase 2/3 • Sponsor: EyeBiotech Ltd. • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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New eye injection could change treatment for wet AMD
Disease control Recruiting nowThis study tests a new drug called tiespectus (MK-8748) against the current standard treatment, aflibercept, for people with wet age-related macular degeneration (AMD). About 960 participants will receive injections into the eye and be followed for a year to see if tiespectus can…
Phase 2/3 • Sponsor: EyeBiotech Ltd. • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Fewer eye injections for wet AMD? new trial tests quarterly faricimab
Disease control Recruiting nowThis study tests whether faricimab (Vabysmo) injections given every 12-16 weeks can maintain stability in people with wet age-related macular degeneration (AMD) after an initial series of loading doses. The trial will enroll 40 adults over 50 with active wet AMD. The main goal is…
Phase 4 • Sponsor: Hospital Authority, Hong Kong • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New Eye-Tracking tech could let AMD patients monitor vision loss from home
Diagnosis Recruiting nowThis study is testing a home-based eye-tracking system called AVIGA to see if it can detect when wet age-related macular degeneration (AMD) comes back. Sixty adults aged 50-99 who are being treated for wet AMD will use the AVIGA device at home, and its accuracy will be compared t…
Sponsor: Tan Tock Seng Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 14:03 UTC
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New 3D ultrasound could reveal hidden stroke risk
Diagnosis Recruiting nowThis study tests a new 3D ultrasound probe to see tiny blood vessels inside fatty plaques in the neck arteries. These vessels can make plaques more likely to rupture and cause a stroke. Ten people who already had a standard ultrasound will get this new 3D scan with a contrast dye…
Sponsor: London North West Healthcare NHS Trust • Aim: Diagnosis
Last updated Jun 27, 2026 12:07 UTC
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Eye fluid clues may predict who benefits from vision-saving injections
Knowledge-focused Recruiting nowThis study analyzes blood and aqueous humor (eye fluid) from 250 people with type 1 choroidal neovascularization—a cause of vision loss—and from controls without the condition. Researchers measure biomarker levels and check whether they correlate with how well patients respond to…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC