Choroidal neovascularization
MONDO:0810000An eye disorder described by the growth of new blood vessels that originate from the choroid through a break in the Bruch membrane into the sub–retinal pigment epithelium (sub-RPE) or subretinal space. Choroidal neovascularization (CNV) is a major cause of visual loss.
26 clinical trials for this condition and its sub-types.
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New drug faricimab takes on leading cause of blindness in nearsighted people
Disease control CompletedThis study tested a drug called faricimab (VABYSMO®) against an existing treatment (ranibizumab) for people with vision loss caused by abnormal blood vessels growing in the back of the eye due to severe nearsightedness. The trial involved 280 participants who received either fari…
Phase: PHASE3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New syringe design makes eye injection easier for doctors
Disease control CompletedThis study tested whether a pre-filled syringe of the medicine SB11 (a biosimilar to ranibizumab) is easy for eye doctors to use. Thirty adults with wet age-related macular degeneration, macular edema from retinal vein occlusion, or myopic choroidal neovascularization received on…
Phase: PHASE2 • Sponsor: Samsung Bioepis Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Eye drug dosing showdown: can fewer injections still control wet AMD?
Disease control CompletedThis study compared two different dosing schedules of brolucizumab (Beovu) in 52 people with wet age-related macular degeneration (AMD) who had not responded well to previous treatment. Participants received the drug as an eye injection either on a fixed schedule or with adjustme…
Phase: PHASE4 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC