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Eye fluid clues may predict who benefits from vision-saving injections

NCT ID NCT04439708

Recruiting now Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study analyzes blood and aqueous humor (eye fluid) from 250 people with type 1 choroidal neovascularization—a cause of vision loss—and from controls without the condition. Researchers measure biomarker levels and check whether they correlate with how well patients respond to anti-VEGF treatment. The goal is to identify biological markers that could guide personalized therapy for this eye disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors predict which patients will respond well to anti-VEGF injections, allowing more personalized treatment for vision loss.
What could go wrong
This is an observational biomarker study, not a treatment trial. It may not find reliable markers, and any findings would need further validation before changing clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

central serous chorioretinopathy choroidal neovascularization hyperaldosteronism macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHOROIDAL NEOVASCULARIZATION MINERALOCORTICOID EXCESS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Foch

    RECRUITING

    Suresnes, 92150, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ophtalmopole Hôpital Cochin

    RECRUITING

    Paris, 75014, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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