Stem cell injection aims to restore vision in dry AMD patients

NCT ID NCT03178149

Recruiting now Disease control Sponsor: Astellas Institute for Regenerative Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a stem cell therapy called ASP7317 for people with geographic atrophy, the advanced form of dry age-related macular degeneration that causes central vision loss. The treatment involves injecting special cells under the retina to replace damaged ones. Participants will take immune-suppressing drugs for a short time to prevent rejection. The main goal is to check safety and tolerability in 42 older adults with moderate to severe vision loss.

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Conditions

The condition(s) this trial relates to.

age-related macular degeneration Geographic Atrophy macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGE-RELATED MACULAR DEGENERATION

Contacts and locations

Locations

Deep Blue Retina
RECRUITING

Southaven, Mississippi, 38671, United States
Emory University Eye Center
RECRUITING

Atlanta, Georgia, 30322, United States
Jules Stein Eye Institute
RECRUITING

Los Angeles, California, 90095, United States
Kaiser Permanente Riverside Medical Center
RECRUITING

Riverside, California, 92505, United States
Mass Eye and Ear Infirmary Ophthalmology Clinical Research Office
WITHDRAWN

Boston, Massachusetts, 02114, United States
Mid-Atlantic Retina
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
NJ Retina
WITHDRAWN

New Brunswick, New Jersey, 08901, United States
Ophthalmic Consultants of Boston
RECRUITING

Boston, Massachusetts, 02114, United States
Retina Consultants of Southwest Florida & National Ophthalmic Research Institute
WITHDRAWN

Fort Myers, Florida, 33912, United States
Retina Foundation of the Southwest
RECRUITING

Dallas, Texas, 75231, United States
Retina Specialty Institute
RECRUITING

Pensacola, Florida, 35203, United States
Retinal Consultants of Arizona LTD, Retinal Research Institute
WITHDRAWN

Phoenix, Arizona, 85053, United States
Spokane Eye Clinical Research
RECRUITING

Spokane, Washington, 99204, United States
Stanford University Byers Eye Institute
RECRUITING

Palo Alto, California, 94303, United States
Tennessee Retina, PC
WITHDRAWN

Nashville, Tennessee, 37203, United States
University Retina and Macula Associates
RECRUITING

Oak Forest, Illinois, 60452, United States
University of Michigan Kellog Eye Center
RECRUITING

Ann Arbor, Michigan, 48105, United States
University of Washington
WITHDRAWN

Seattle, Washington, 98104, United States
Valley Retina Institute
COMPLETED

McAllen, Texas, 78503, United States

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