AGE-RELATED MACULAR DEGENERATION

This study compared two different eye scanning methods to monitor treatment for wet age-related macular degeneration. Researchers tested whether a newer scanning technique called OCT angiography could help doctors better time treatment injections compared to the standard OCT scan…

This study tested two different schedules for giving an eye injection called brolucizumab to people with 'wet' age-related macular degeneration (AMD) who were already receiving treatment. The goal was to see if starting with a series of three injections (a 'loading' phase) was be…

This study tested whether the oral antibiotic minocycline could safely slow the progression of geographic atrophy, an advanced and untreatable form of dry age-related macular degeneration that causes central vision loss. Participants aged 55+ with the condition took minocycline p…

This study tested whether carbidopa-levodopa, a common Parkinson's disease medication, could help control 'wet' age-related macular degeneration (AMD), a major cause of vision loss. Researchers gave the oral medication to 20 participants with newly diagnosed wet AMD to see if it …

This study tested whether giving people with age-related macular degeneration (AMD) personalized information about their genetic risk and/or coaching could help them stick to recommended lifestyle changes. Researchers wanted to see if these strategies were better than standard ad…

This study tested a robotic tool designed to help eye surgeons perform a delicate procedure. The robot held a tiny needle steady to inject a clot-dissolving drug under the retina in patients with bleeding caused by age-related macular degeneration. The goal was to see if the robo…

This study tested whether a daily capsule called ALK-001 could slow the progression of geographic atrophy, a severe form of age-related macular degeneration that causes permanent vision loss. About 300 people with this condition were randomly assigned to receive either the study …

This study followed patients who had already completed a previous trial to check the long-term safety of avacincaptad pegol, an eye injection for geographic atrophy. Geographic atrophy is an advanced form of age-related macular degeneration that causes permanent vision loss. The …

This study tested whether a common Parkinson's disease pill (carbidopa-levodopa) could help people with 'wet' age-related macular degeneration (AMD), a major cause of vision loss. Researchers gave the drug to 35 participants who were also receiving standard eye injections, to see…

This study tested if regular injections of a drug (aflibercept) into the eye could prevent a common eye disease from turning into its more severe, vision-threatening form. It involved 128 people at high risk for this progression because their other eye already had the severe form…

This study tested if a steroid eye drop called loteprednol could reduce pain after eye injections for age-related macular degeneration. 64 patients received either the steroid drop or artificial tears after their standard injection. Researchers called patients to track their pain…

This study looked back at existing medical records and eye scans from 60 patients with geographic atrophy, a severe form of dry macular degeneration that causes vision loss. The goal was to understand which specific features of the retina seen on scans are linked to faster vision…

This study aimed to understand why some patients with wet age-related macular degeneration don't respond well to standard eye injections. Researchers measured specific proteins in the fluid inside the eyes of 100 patients. The goal was to identify biological markers that might pr…

This study aimed to see if detailed eye scans could predict vision loss in people at risk for age-related macular degeneration (AMD). Researchers followed 470 participants for five years, using special imaging to track tiny changes in the back of the eye. The goal was to find ear…

This study aimed to better understand how early age-related macular degeneration (AMD) changes over time. Researchers followed about 500 adults aged 55 and older, some with early AMD, some with a specific type called RPD, and some with healthy eyes, for up to 5 years. They regula…

This study aimed to understand the link between poor night vision and the early stages of age-related macular degeneration (AMD), a common cause of vision loss in older adults. Researchers followed 556 participants, including older adults with and without early AMD and a younger …

This study aimed to better understand how geographic atrophy, an advanced form of age-related macular degeneration, naturally progresses over time. It observed 20 adults aged 55 and older with this condition for nearly four years, tracking changes in their eyes through regular ex…

This study wanted to see if telling healthy people their genetic risk for age-related macular degeneration (AMD) would motivate them to improve their diet and nutrient levels. Researchers enrolled 80 Caucasian adults without AMD, gave them a genetic test, and then tracked changes…