Eye imaging study aims to predict who will lose sight from AMD

NCT ID NCT05698316

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study collected eye images from 1,000 people with intermediate age-related macular degeneration (AMD) to create a detailed database. Researchers will analyze these images to find signs that predict whether the disease will worsen to advanced stages. The goal is to improve early detection and monitoring, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors predict which patients with intermediate AMD will develop vision loss, enabling earlier monitoring or treatment.
What could go wrong
This is an observational study that builds a database, not a treatment trial. It may not lead to immediate clinical changes, and the predictive models need further validation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AIBILI-CEC (AIBILI- Clinical Trials Centre)

    Coimbra, Portugal

  • Clinical Eye Research Centre - St. Paul's Eye Unit, Royal Liverpool University Hospital

    Liverpool, United Kingdom

  • Clinical Trial Unit, Dep. Ophth., Gloucestershire Hospitals NHS Foundation Trust

    Cheltenham, United Kingdom

  • Clínica Oftalmológica AIKEN / Fundación Aiken de la Comunitat Valenciana

    Valencia, Spain

  • Department of Ophthalmology Justus/Liebig/University/Giessen

    Giesen, Germany

  • Department of Ophthalmology Porto Medical School / Hospital S. João

    Porto, Portugal

  • Department of Ophthalmology Radboud University Medical Centre Nijmegen

    Nijmegen, Netherlands

  • Department of Ophthalmology St. Franziskus/Hospital Münster

    Münster, Germany

  • Department of Ophthalmology University of Bonn

    Bonn, Germany

  • Department of Ophthalmology University of Freiburg

    Freiburg im Breisgau, Germany

  • Department of Ophthalmology University of Muenster Medical Center

    Münster, Germany

  • Department of Ophthalmology University of Udine

    Udine, Italy

  • Department of Ophthalmology, University Hospital, Nantes

    Nantes, France

  • Espaço Médico de Coimbra

    Coimbra, Portugal

  • Eye Clinic Sulzbach, Knappschaft Hospital Saar

    Sulzbach, Germany

  • Eye Unit, University Hospital Maggiore della Carità

    Novara, Italy

  • Institut Català de Retina (ICR), Clinical Trial Unit

    Barcelona, Spain

  • Institut de la Màcula Centro Médico Teknon

    Barcelona, Spain

  • Instituto de Oftalmologia Dr. Gama Pinto

    Lisbon, Portugal

  • Medical Retina Service, Operative Unit Ophthalmology / MultiMedica Spa (IRCCSMM)

    Milan, Italy

  • NIHR Moorfields Clinical Research Facility, Moorfields Eye Hospital, NHS Foundation Trust

    London, United Kingdom

  • Royal Victoria Eye and Ear Research Foundation

    Dublin, Ireland

  • Swiss Visio Retina Research Center, Swiss Visio Montchoisi

    Lausanne, Switzerland

  • University Hospital Basel, University Eye Clinic, Basel

    Basel, Switzerland

  • Valles Ophthalmology Research, S.L.

    Barcelona, Spain

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