Can a steroid drop take the sting out of eye injections?
NCT ID NCT05542381
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested whether a steroid eye drop (loteprednol) can reduce pain after intravitreal injections for age-related macular degeneration. 64 participants received either the steroid drop or artificial tears right after their injection. Pain was tracked by phone over a week. The goal is to find a simple way to improve comfort after these common eye procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Loteprednol etabonate ophthalmic gel (corticosteroid eye drop)
What this could lead to
If it works, this could give doctors a simple way to reduce pain after routine eye injections for macular degeneration.
What could go wrong
This is a small, completed study (64 people) comparing the steroid to artificial tears. The results may not apply to everyone, and steroids can raise eye pressure in some patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Vistar Eye Center
Roanoke, Virginia, 24019, United States