Eye scans may predict who loses sight from macular degeneration

NCT ID NCT00734487

Completed Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 470 people with age-related macular degeneration (AMD) to see if special eye scans (SDOCT) can predict vision loss and disease worsening. Participants were already in the AREDS 2 trial and had moderate to high risk of progression. Researchers tracked changes in the retina over time to find early warning signs of advanced AMD.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict who will lose vision from macular degeneration, allowing earlier monitoring or treatment.
What could go wrong: This is an observational study, not a treatment trial. It may not find clear predictors, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

age-related macular degeneration macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGE-RELATED MACULAR DEGENERATION

Contacts and locations

Locations

Devers Eye Center

Portland, Oregon, 97210, United States
Duke University Eye Center

Durham, North Carolina, 27705, United States
Emory University Eye Center

Atlanta, Georgia, 30322, United States
National Eye Institute

Bethesda, Maryland, 20892, United States

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