ACUTE MYOCARDIAL INFARCTION

This study looked at whether doing cardiac rehab at home, or a mix of home and clinic sessions, works as well as going to the clinic for all sessions. 206 heart patients participated, using a mobile health platform and home exercise. The goal was to see if flexible options could …

This study looked at whether using only ticagrelor (a blood thinner) after heart attack stenting is safe, instead of the usual two-drug combination. It included 200 adults who had a stent placed during a heart attack. The main goal was to check for serious heart problems or stent…

This study tested a new treatment for people who had a severe heart attack and still have weak heart pumping. Doctors took the patients' own blood stem cells, grew more of them in a special machine, and injected them into the heart. The goal was to see if this could improve heart…

This study tested a single intravenous infusion of stem cells (PROCHYMAL) in 220 adults who had their first heart attack within the prior week. The goal was to see if the treatment could safely improve heart function, as measured by MRI scans at 3 months. Participants were random…

This study tested whether injecting a patient's own bone marrow stem cells into the heart's arteries could improve heart function after a heart attack. 90 adults with reduced heart pumping ability were randomly assigned to receive either stem cells plus standard care or standard …

This study tested two types of exercise training—high-intensity interval training (HIIT) and moderate continuous training (MICT)—against standard physical activity advice in 188 people who had a heart attack. The goal was to see which approach best improves fitness and reduces he…

This study tested whether a smartphone app and regular phone calls could help people with heart or lung disease complete rehabilitation at home instead of going to a clinic. The program included exercise tracking, education, and counseling over 12 weeks. Researchers wanted to see…

This study tested a new medicine called FDY-5301 in 120 people having a severe heart attack (STEMI). Participants received either the drug or a placebo during a procedure to open blocked arteries. The main goal was to see if the drug could reduce dangerous heart rhythm problems a…

This study tested whether the diabetes drug dapagliflozin can reduce inflammation and improve outcomes in people with type 2 diabetes who recently had a heart attack. Researchers gave 143 patients either dapagliflozin or standard care for 6 months. They measured heart complicatio…

This study tested whether adding evolocumab, a drug that lowers bad cholesterol, to standard care helps people who recently had a heart attack. The goal was to see if it reduces cholesterol and inflammation in the heart and blood vessels. 100 adults aged 25 to 90 who had a specif…

This study tested a single injection of FDY 5301 in over 2,300 people who had a severe type of heart attack (anterior STEMI) and were getting emergency artery-opening treatment. The goal was to see if the drug could lower the chance of dying or developing heart failure within a f…

This study looked at whether using different blood test cutoffs for men and women can better diagnose heart attacks. Current tests use the same cutoff for both sexes, which may miss heart attacks in women and over-diagnose them in men. Researchers tested new sex-specific cutoffs …

This study tested a new blood test called SpinChip hs-cTnI that measures troponin, a protein released during a heart attack. Researchers wanted to see if this test could accurately diagnose heart attacks in 1,551 adults arriving at the emergency room with chest pain or other symp…

This study measured troponin I levels in 1355 healthy adults to determine normal ranges for a new rapid test called SpinChip hs-cTnI. Troponin is a protein released during a heart attack, and having accurate normal values helps doctors diagnose heart attacks more reliably. The te…

This pilot study tested whether a common blood test for troponin, a heart damage marker, can tell if a heart attack involves bleeding in the heart muscle. Researchers measured troponin levels in 227 patients after they had a heart attack and compared those with and without bleedi…

This study looked at how well two types of stents (small mesh tubes) placed in heart arteries after a heart attack become covered by the body's own cells. 22 people who had a heart attack were randomly assigned to get either a SYNERGY stent or a bioresorbable scaffold. Doctors us…

This study looked at 100 people who had a heart attack to see if certain inflammation markers in the blood could predict who might die or develop heart failure within 6 months. Researchers measured these markers at several time points after the attack. The goal was to better unde…

This completed study tracked 832 heart attack patients in China who developed new-onset atrial fibrillation during their hospital stay. Researchers used continuous heart monitoring to see how the amount of AFib affected risks like death, another heart attack, or heart failure. Th…

This completed study looked at 250 adults who had a severe type of heart attack (STEMI) treated with a stent. Researchers used portable heart monitors to check how often dangerous heart rhythms occurred in people whose heart attack involved bleeding. The goal was to better unders…

This completed study looked at over 6,000 heart attack patients to see how different antiplatelet medications affect the risk of bleeding inside the heart. Researchers compared outcomes like heart-related events, bleeding complications, and death within 30 days. The goal is to he…

This study looked at blood clots from 380 people who had a heart attack or sudden cardiac death. Researchers wanted to see if the age and makeup of the clot could explain why some people die suddenly while others survive. They compared clots from sudden death victims, heart attac…

This study looked at 250 people who had a severe type of heart attack involving bleeding into the heart muscle. Researchers tested whether a measurement called the wall strain index ratio, taken from a heart MRI, could identify areas of the heart at risk of tearing (rupture). The…

Researchers have created a prediction score to estimate the chance of a hemorrhagic (bleeding) heart attack in patients before they undergo emergency artery-opening treatment. The study involved 252 adults having their first heart attack and treated with primary PCI. The goal is …

This study looked at whether a technique called postconditioning, done during angioplasty to reopen blocked heart arteries, can reduce damage to the heart muscle. 44 adults having their first heart attack took part. The researchers used MRI scans to measure the area of blocked sm…

This completed study looked at 1,000 heart attack patients to understand why some have no standard risk factors like smoking, high blood pressure, or diabetes. Researchers compared these 'SMuRF-less' patients to those with risk factors, examining their medical history, lab tests,…

This completed study looked at medical records from over 24,000 people across the United States who had a heart attack. The goal was to find out how often a specific complication called hemorrhagic myocardial infarction (bleeding inside the heart muscle) occurs. Researchers also …