New shot aims to save hearts after major attack
NCT ID NCT04837001
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested a single injection of FDY 5301 in over 2,300 people who had a severe type of heart attack (anterior STEMI) and were getting emergency artery-opening treatment. The goal was to see if the drug could lower the chance of dying or developing heart failure within a few months. The trial is complete, but results have not been shared yet.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- FDY 5301 (a single intravenous injection)
- What this could lead to
- If it works, this could reduce the risk of dying or developing heart failure after a major heart attack.
- What could go wrong
- This is a completed phase 3 trial, but results are not yet published. The drug may not show a clear benefit over placebo, and any new treatment carries unknown risks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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4. Military Clinical Hospital with Polyclinic SP ZOZ
Wroclaw, 50-981, Poland
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Allina Health System
Minneapolis, Minnesota, 55407, United States
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Bajcsy-Zsilinszky Kórház és Rendelőintézet IV. Belgyógyászat és Kardiológia, Intenzív Coronaria Egység, Haemodinamikai Osztály
Budapest, 1106, Hungary
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Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Oktatókórház
Miskolc, 3526, Hungary
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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Budai Irgalmasrendi Kórház
Budapest, 1023, Hungary
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Bács-Kiskun Vármegyei Oktatókórház
Kecskemét, 6000, Hungary
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Center for Invasive Cardiology
Krosno, 38-400, Poland
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Central Clinical Hospital of the Medical University of Łódź
Lodz, 92-213, Poland
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Centro Hospitalar Universitário Lisboa Central
Lisbon, 1169-024, Portugal
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Centro Hospitalar Universitário Lisboa Norte
Lisbon, 1649-035, Portugal
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Centro Hospitalar Universitário do Porto
Porto, 4099-001, Portugal
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Centro Hospitalar Vila Nova de Gaia/Espinho
Vila Nova de Gaia, 4434-502, Portugal
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Centro Hospitalar e Universitário de Coimbra
Coimbra, 3000-075, Portugal
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Fejér Vármegyei Szent György Egyetemi Oktató Kórház
Székesfehérvár, 8000, Hungary
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Galilee Medical Center
Nahariya, 2210001, Israel
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Gottsegen György Országos Kardiológiai Intézet
Budapest, 1096, Hungary
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Hadassah Ein Karem Medical Center
Jerusalem, 9112001, Israel
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Harbor-UCLA Medical Center
Torrance, California, 90502, United States
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Hospital Garcia da Orta
Almada, Setúbal District, 2805-267, Portugal
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Hospital de Braga
Braga, 4710-243, Portugal
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Independent Public Provincial Hospital
Zamość, 22-400, Poland
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Independent Public Specialist Hospital of the West st. John Paul II
Grodzisk Mazowiecki, 05-825, Poland
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Lehigh Valley Hospital
Allentown, Pennsylvania, 18103, United States
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Meir Medical Center
Kfar Saba, 4428164, Israel
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Provincial Specialist Hospital in Wrocław
Wroclaw, 51-124, Poland
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Pécsi Tudományegyetem Klinikai Kozpönt Szívgyógyászati Klinika
Pécs, 7624, Hungary
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Rabin Medical Center, Beilinson Hospital
Petah Tikva, 4941492, Israel
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Rambam Health Care Campus
Haifa, 3109601, Israel
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SP ZOZ Szpital Uniwersytecki w Krakowie
Krakow, 30-688, Poland
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Samodzielny Publiczny Szpital Kliniczny nr 4 w Lublinie
Lublin, 20-954, Poland
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Scanmed Centrum Kardiologii Kutno
Kutno, 99-300, Poland
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Semmelweis Egyetem Városmajori Szív- és Érgyógyászati Klinika
Budapest, 1122, Hungary
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Shaare Zedek Medical Center
Jerusalem, 91301, Israel
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Shamir (Assaf Harofeh) Medical Center
Be’er Ya‘aqov, 7033001, Israel
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Sheba Medical Center
Ramat Gan, 5265601, Israel
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Somogy Vármegyei Kaposi Mór Oktató Kórház, Kardiológiai Osztály
Kaposvár, 7400, Hungary
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Sourasky Medical Center
Tel Aviv, 6423906, Israel
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Southlake Regional Health Center
Newmarket, Ontario, L3Y 2P9, Canada
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Sparrow Clinical Research Institute
Lansing, Michigan, 48912, United States
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Szabolcs-Szatmár-Bereg Vármegyei Oktatókórház, Nyíregyházi Jósa András Tagkórház
Nyíregyháza, 4400, Hungary
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University of Florida Health
Jacksonville, Florida, 32209, United States
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Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu
Wroclaw, 50-556, Poland
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Uniwersytecki Szpital Kliniczny im. Wojskowej Akademii Medycznej
Lodz, 90-549, Poland
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Uniwersytecki Szpital Kliniczny w Białymstoku
Bialystok, 15-276, Poland
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Uniwersyteckie Centrum Kliniczne
Gdansk, 80-214, Poland
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Vas Vármegyei Markusovszky Egyetemi Oktatókórház
Szombathely, 9700, Hungary
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Wojewódzki Szpital Zespolony im. L. Rydygiera w Toruniu
Torun, 87-100, Poland
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Wojskowy Szpital Kliniczny z Poliklinika SPZOZ w Lublinie
Lublin, 20-049, Poland
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Zala Megyei Szent Rafael Kórház
Zalaegerszeg, 8900, Hungary
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Ziv Medical Center
Safed, 13110, Israel
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Észak-Pesti Centrumkórház - Honvédkórház
Budapest, 1134, Hungary
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Other studies related to the condition(s) this trial covers.
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