New heart scan may predict deadly rupture after heart attack
NCT ID NCT06450912
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looked at 250 people who had a severe type of heart attack involving bleeding into the heart muscle. Researchers tested whether a measurement called the wall strain index ratio, taken from a heart MRI, could identify areas of the heart at risk of tearing (rupture). The goal was to find a better way to predict this rare but often fatal complication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple imaging test to identify patients at highest risk of heart rupture after a heart attack, allowing for closer monitoring or earlier intervention.
- What could go wrong
- This is an observational study, not a treatment trial. The biomarker needs further validation in larger, diverse populations before it can be used in routine care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Krannert Cardiovascular Research Center, Indiana University School of Medicine
Indianapolis, Indiana, 46202, United States
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