ACUTE LYMPHOBLASTIC LEUKEMIA
Clinical trials for ACUTE LYMPHOBLASTIC LEUKEMIA explained in plain language.
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Experimental cell therapy takes on tough leukemia
Disease control Not yet recruitingThis early-phase trial tests a new treatment called TSLPR-CART for adults with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to treatment. The therapy uses a patient's own immune cells, modified in a lab to target a protein called TSLPR found on …
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 01:00 UTC
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Three-Drug cocktail aims to tame transplant complications in blood cancer patients
Disease control Not yet recruitingThis trial investigates whether adding bortezomib and sitagliptin to standard post-transplant cyclophosphamide can prevent graft-versus-host disease (GvHD) in adults with blood cancers receiving a stem cell transplant. Participants receive the drug combination after transplant, w…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Northwell Health • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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New drug cocktail aims to boost transplant success in tough leukemias
Disease control Not yet recruitingThis phase 2 trial tests whether adding two drugs (SHR2554 and azacitidine) to standard chemotherapy before a stem cell transplant can help people with high-risk or relapsed/refractory acute leukemia or myelodysplastic syndromes. About 180 participants aged 15-60 will be randomly…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New pill takes on tough blood cancers in first human trial
Disease control Not yet recruitingThis early-stage study tests a new tablet, FXS0683, in 228 adults with blood cancers like lymphoma or leukemia that returned or didn't respond to standard therapy. The main goals are to check safety, find the best dose, and see if the drug shrinks tumors. Participants will be clo…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New hope for young leukemia patients: experimental drug combo targets resistant cancer
Disease control Not yet recruitingThis study tests a new drug called asciminib, given with chemotherapy and later with another drug (blinatumomab), in children, teens, and young adults up to age 30 who have a type of leukemia (Ph+ or Ph-like ALL) that has come back or not responded to treatment. The goal is to fi…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Could early antibiotic stop be safe for kids with cancer?
Disease control Not yet recruitingThis trial looks at whether children with cancer who develop a fever and low white blood cells can safely stop antibiotics earlier than usual. About 136 children will be randomly assigned to either stop antibiotics within 24 hours or continue standard treatment. The goal is to se…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE4 • Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New shot aims to stop hidden leukemia in its tracks
Disease control Not yet recruitingThis study tests whether a drug called blinatumomab, given as a simple injection under the skin, can control small amounts of leftover leukemia cells (called measurable residual disease, or MRD) in adults with B-cell acute lymphoblastic leukemia. The goal is to prevent the cancer…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New drug cocktail aims to stop leukemia relapse after transplant
Disease control Not yet recruitingThis study tests whether adding SHR2554 and azacitidine to standard chemotherapy before a stem cell transplant can lower the chance of cancer returning in people aged 15-60 with high-risk or relapsed leukemia or myelodysplastic syndromes. Half the participants will get the new dr…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New hope for leukemia patients: immunotherapy added to standard care
Disease control Not yet recruitingThis study tests a new treatment plan for adults up to 65 years old with a type of leukemia called Ph-negative ALL. The goal is to see if adding an immunotherapy drug called blinatumomab improves survival compared to the previous treatment plan. About 330 participants will receiv…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: NA • Sponsor: PETHEMA Foundation • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Antibiotic shield may protect young leukemia patients from dangerous infections
Disease control Not yet recruitingThis study tests whether giving the antibiotic levofloxacin to children with acute lymphoblastic leukemia (ALL) can delay or prevent the first episode of febrile neutropenia (fever with low white blood cells) during early chemotherapy. About 124 children aged 1 to 18 will receive…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE4 • Sponsor: Gadjah Mada University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New drug combo aims to finish off hidden leukemia cells in high-risk patients
Disease control Not yet recruitingThis study tests a new drug called BEBT-908 combined with chemotherapy in adults with a rare, high-risk form of acute lymphoblastic leukemia (ALL) who are in remission but still have tiny amounts of cancer cells detectable. The goal is to see if the combo can clear those leftover…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New hope for young leukemia patients: targeted chemo combo aims to boost treatment success
Disease control Not yet recruitingThis study is for adolescents and young adults (ages not specified) with newly diagnosed Philadelphia chromosome-negative acute lymphoblastic leukemia (ALL). Researchers want to see if a specific combination of chemotherapy drugs plus the immunotherapy blinatumomab helps more pat…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Promising drug cocktail targets tough childhood cancers
Disease control Not yet recruitingThis trial tests a combination of three drugs—capivasertib, venetoclax, and dexamethasone—in children and young adults with relapsed or refractory acute lymphoblastic leukemia (ALL) or lymphoblastic lymphoma (LBL). The study has two phases: first, to find the safest dose, and sec…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1, PHASE2 • Sponsor: Princess Maxima Center for Pediatric Oncology • Aim: Disease control
Last updated Jun 26, 2026 17:34 UTC
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Light therapy may shield kids with cancer from chemo mouth sores
Prevention Not yet recruitingThis study tests whether light therapy (photobiomodulation) can prevent mouth sores in children receiving chemotherapy. Fifty children aged 0-30 will receive daily light treatments during hospital stays and at home. Researchers will check if the therapy is easy to use and accepta…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Prevention
Last updated Jun 27, 2026 14:01 UTC
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Exercise during chemo: new study tests strength training for children with leukemia
Symptom relief Not yet recruitingThis study tests whether a 9-week strength training program using resistance bands and body weight exercises is practical for children aged 6-21 newly diagnosed with acute lymphoblastic leukemia or lymphoblastic lymphoma. The program combines at-home exercises with optional Zoom …
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Healing harmonies: music therapy aims to ease stem cell transplant recovery
Symptom relief Not yet recruitingThis study tests an online music therapy program that combines mindfulness and music to help people recovering from stem cell transplants for blood cancers. Researchers want to see if it can improve quality of life, reduce pain, fatigue, anxiety, and depression, and possibly spee…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: NA • Sponsor: University of Miami • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Shock therapy? electrical acupoints may soothe chemo pain in kids with leukemia
Symptom relief Not yet recruitingThis study tests if a gentle, non-invasive electrical stimulation on specific acupoints can reduce nerve pain caused by chemotherapy in children aged 10-17 with acute lymphoblastic leukemia. The treatment is given for 8 weeks, and researchers will check if it helps with pain, mov…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: NA • Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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New study tracks hidden dangers of common leukemia drug
Knowledge-focused Not yet recruitingThis study will follow 200 children with acute lymphoblastic leukemia or lymphoma to learn more about the short- and long-term side effects of asparaginase drugs. Researchers will track how often serious toxicities occur during standard treatment and a newer therapy called SJALL2…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jul 02, 2026 01:00 UTC
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Can a simple social check improve leukemia care?
Knowledge-focused Not yet recruitingThis study looks at whether screening adults with leukemia for social needs (like housing or food) and offering early social work help is practical and helpful. About 80 newly diagnosed patients will either get the screening and consultation or usual care. The goal is to see if t…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Scientists investigate how immune cells fight leukemia
Knowledge-focused Not yet recruitingThis study will collect blood and bone marrow samples from 55 adults with acute leukemia or myelodysplastic syndrome. Researchers want to understand how natural killer (NK) cells interact with cancer cells over time. The goal is to identify genetic markers and immune patterns tha…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Italian study to track CAR-T success in leukemia patients
Knowledge-focused Not yet recruitingThis observational study will follow 107 children and adults with B-cell acute lymphoblastic leukemia who are treated with approved CAR-T cell therapies in Italy. Researchers will collect data from medical records to see how many patients achieve a response. The goal is to unders…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Leukemia drug timing under the microscope: new study aims to improve dosing
Knowledge-focused Not yet recruitingThis study looks at how long the drug calaspargase pegol stays at effective levels in the blood of children and young adults with acute lymphoblastic leukemia or lymphoma. Researchers will measure drug activity and check for links to side effects. The goal is to better understand…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New study aims to catch late effects in childhood cancer survivors
Knowledge-focused Not yet recruitingThis study will create a structured follow-up program for 400 children and young adults who have survived blood cancers like leukemia and lymphoma. Researchers want to better track and understand long-term health problems that can appear years after treatment. The goal is to impr…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: The Children's Hospital of Zhejiang University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New study aims to predict deadly infections in blood cancer patients
Knowledge-focused Not yet recruitingThis study looks at blood cancer patients who carry drug-resistant bacteria in their gut. Researchers want to find out who is most likely to get a serious infection from these bacteria. They will collect rectal swabs and track patients for 90 days to build a prediction tool. The …
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New study aims to predict bleeding and clotting risks in cancer patients
Knowledge-focused Not yet recruitingThis observational study will measure how well the body breaks down blood clots in 150 cancer patients (with blood cancers or solid tumors) who also have clotting issues. Researchers will take extra blood samples during routine care to look for markers that might predict bleeding…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC