ACUTE LYMPHOBLASTIC LEUKEMIA

This study is testing a new treatment protocol for adults with a specific type of acute lymphoblastic leukemia (ALL). Researchers want to see if adding an immunotherapy drug called blinatumomab to chemotherapy leads to better survival rates than the older chemotherapy-only approa…

This trial is testing a new combination of three drugs—capivasertib, venetoclax, and dexamethasone—for children and young adults whose leukemia or lymphoma has come back or hasn't responded to standard treatments. The main goals are to find the safest dose and see if this combina…

This study is testing whether a weekly weight-loss medication (Tirzepatide) combined with a remote, supervised exercise program can help adult survivors of childhood leukemia lose weight and improve their heart and metabolic health. The 28-week program aims to see if participants…

This study is testing a combination of chemotherapy and an immunotherapy drug (blinatumomab) to treat a type of blood cancer called acute lymphoblastic leukemia (ALL) in adolescents and young adults. The goal is to see if this specific treatment plan is safe and effective for thi…

This study is testing whether adding specific targeted drugs to standard chemotherapy works better for adults with a hard-to-treat type of leukemia called 'Ph-like ALL.' Doctors will give patients either olverembatinib or ruxolitinib based on their specific genetic test results, …

This study is testing whether giving the drug blinatumomab as an injection under the skin can help control very low levels of leukemia cells and prevent the cancer from coming back. It will involve about 40 adults with B-cell acute lymphoblastic leukemia who are in remission but …

This study is testing whether daily text message reminders can help teenagers and young adults with acute lymphoblastic leukemia (ALL) remember to take their oral chemotherapy pills during long-term maintenance treatment. Researchers will compare medication-taking habits between …

This study is testing whether adding a new drug called BEBT-908 to standard chemotherapy can help patients with a specific type of acute lymphoblastic leukemia. It focuses on adults who are in remission but still have tiny amounts of cancer cells detectable in their body. The goa…

This study is for children and adults (ages 3-65) with a type of blood cancer called B-cell acute lymphoblastic leukemia (ALL). The goal is to see if giving a second, different CAR T-cell treatment (targeting CD22) to people who are already in remission after their first CAR T-ce…

This study is testing a new combination of drugs for children and young adults (ages 1-30) whose acute lymphoblastic leukemia (ALL) has come back or hasn't responded to other treatments. The goal is to see if adding a new targeted drug (asciminib) to a lower-dose chemotherapy and…

This study is testing whether a new genetic sequencing test called ChromoSeq® can provide faster and more accurate diagnosis for children and young adults with acute lymphoblastic leukemia (ALL). Researchers will collect blood and bone marrow samples from 60 patients to see if th…

This study aims to see if giving the antibiotic levofloxacin can help prevent or delay a dangerous condition called febrile neutropenia in children with acute lymphoblastic leukemia (ALL) during their initial chemotherapy. Researchers will compare the antibiotic to a placebo (a d…

This study aims to create and test a structured follow-up system for children and young adults who have survived blood cancers like leukemia and lymphoma. It will track 400 survivors for three years to understand the long-term health problems they face and see if a new, organized…