ACUTE LYMPHOBLASTIC LEUKEMIA
Clinical trials for ACUTE LYMPHOBLASTIC LEUKEMIA explained in plain language.
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Promising leukemia combo trial for kids ends early
Disease control TerminatedThis study tested a drug called isatuximab added to standard chemotherapy for children aged 28 days to under 18 years whose leukemia (ALL or AML) had returned or stopped responding to treatment. The goal was to see if the combination could help achieve complete remission. The tri…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Sanofi • Aim: Disease control
Last updated May 17, 2026 00:31 UTC
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Leukemia drug trial halted early, but data may guide future care
Disease control TerminatedThis study tested a drug called calaspargase pegol in adults aged 22 and older with a specific type of acute lymphoblastic leukemia (ALL) that lacks the Philadelphia chromosome. The goal was to find the right dose and check for side effects. The trial was stopped early, but the i…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2, PHASE3 • Sponsor: Institut de Recherches Internationales Servier • Aim: Disease control
Last updated May 17, 2026 00:27 UTC
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Blood cancer transplant study tests safer GVHD prevention
Disease control TerminatedThis study looked at people with blood cancers receiving a stem cell transplant from an unrelated donor. The goal was to compare two drug combinations (cyclosporine plus sirolimus with either MMF or post-transplant cyclophosphamide) to prevent graft-versus-host disease (GVHD), a …
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 17, 2026 00:27 UTC
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Promising leukemia drug tested in kids, but study stopped early
Disease control TerminatedThis study tested a drug called inotuzumab ozogamicin (Besponsa) in children with a type of leukemia (B-ALL) that still had small amounts of cancer cells after treatment. The goal was to see if the drug could wipe out those leftover cells. Only 5 children took part before the stu…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 17, 2026 00:25 UTC
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Targeted drug combo shows promise in blood cancer transplant study
Disease control TerminatedThis study tested whether adding the targeted drug inotuzumab ozogamicin before and after a stem cell transplant could help control leukemia and lymphoma. The drug attaches to cancer cells and delivers chemotherapy directly to them. The study included 15 people aged 12 to 75 with…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Promising combo for tough leukemia falls short in early trial
Disease control TerminatedThis study tested whether adding the drug ponatinib to a standard chemotherapy mix plus venetoclax could help people whose T-cell acute lymphoblastic leukemia (T-ALL) had come back or stopped responding to treatment. Only 4 people took part before the study was stopped early. The…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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Experimental Dual-Target CAR-T therapy for tough leukemia shows early promise but study halted
Disease control TerminatedThis early-stage study tested a personalized cell therapy (CAR-T) that targets two markers (CD19 and CD20) on leukemia cells. It included 5 patients with B-cell acute lymphoblastic leukemia that had returned or not responded to standard treatments. The main goal was to check safe…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 05, 2026 11:54 UTC
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Vitamins tested to fix liver damage from leukemia drugs
Symptom relief TerminatedThis study tested whether levocarnitine (an amino acid) and vitamin B complex could help lower high bilirubin levels caused by two leukemia drugs, PEG-asparaginase and inotuzumab ozogamicin. The trial planned to enroll 10 adults with acute lymphoblastic leukemia, but it was termi…
Matched conditions: ACUTE LYMPHOBLASTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 17, 2026 00:26 UTC