Promising combo for tough leukemia falls short in early trial

NCT ID NCT05268003

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 21 times

Summary

This study tested whether adding the drug ponatinib to a standard chemotherapy mix plus venetoclax could help people whose T-cell acute lymphoblastic leukemia (T-ALL) had come back or stopped responding to treatment. Only 4 people took part before the study was stopped early. The goal was to see how many patients achieved complete remission or near-complete remission.

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Contacts and locations

Locations

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.