Can vitamin supplements fix Chemo-Related liver problems?

NCT ID NCT03564678

Terminated Symptom relief Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 2 trial tested whether levocarnitine and vitamin B complex could help lower high liver enzyme levels caused by chemotherapy drugs in adults with acute lymphoblastic leukemia. The study planned to enroll 10 participants but was terminated early. The goal was to see if these supplements could normalize or significantly reduce bilirubin levels within 11 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Levocarnitine and vitamin B complex
What this could lead to: If it works, this could offer a way to manage liver side effects from certain leukemia treatments, helping patients stay on their cancer therapy.
What could go wrong: This was a very small, early-phase trial that was terminated, so results are limited. The supplements may not effectively lower liver enzyme levels for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia hyperbilirubinemia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE LYMPHOBLASTIC LEUKEMIA HYPERBILIRUBINEMIA

Contacts and locations

Locations

M D Anderson Cancer Center

Houston, Texas, 77030, United States

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