Antibiotic shield may protect young leukemia patients from dangerous infections

NCT ID NCT07320534

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving the antibiotic levofloxacin to children with acute lymphoblastic leukemia (ALL) can delay or prevent the first episode of febrile neutropenia (fever with low white blood cells) during early chemotherapy. About 124 children aged 1 to 18 will receive either levofloxacin or a placebo daily. Researchers will track how long it takes for fever or serious infection to occur, and monitor for side effects. The goal is to see if this preventive approach can reduce infection-related complications during treatment.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia Febrile Neutropenia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • RSUP dr Sardjito

    Sleman, DI Yogyakarta, Indonesia

    Contact Phone: •••-•••-•••• Email: •••••@•••••