Urinary tract infection

This trial compares removing a urinary catheter on day 3 versus day 6 after a living donor kidney transplant. The goal is to see if earlier removal reduces urinary tract infections within 30 days without causing more complications like urine leaks. The study involves 172 adult ki…

This study looks at how well women with low estrogen (like after menopause) stick to using vaginal estrogen treatments to prevent repeat urinary tract infections. About 111 women will be randomly assigned to use a cream, tablet, or ring. Researchers will track adherence over 6 mo…

This study tests the safety of an antibiotic called Vabomere in children aged 3 months to 12 years who have complicated urinary tract infections, including kidney infections. The children receive the medicine through an IV while in the hospital. Researchers monitor for side effec…

This study looks at two drug combinations to treat BK virus infection in kidney transplant recipients. BK virus can cause the new kidney to fail. The trial compares everolimus with a lower dose of tacrolimus versus a lower dose of tacrolimus plus leflunomide in 50 adults whose vi…

This study aims to find out if 5 days of antibiotics works as well as 10 days for children hospitalized with pneumonia, skin infections, or urinary tract infections. About 1,200 children will be randomly assigned to either a 5-day or 10-day course, with some receiving a placebo a…

This study aimed to see if a special blood filter (Seraph 100) could reduce BK virus levels in kidney transplant patients with high viral loads. It planned to enroll adults with a BK virus level of 10,000 IU/mL or higher who already had dialysis access. However, the trial was wit…

This study tests whether taking a probiotic (a 'good' bacteria) can help women who get frequent urinary tract infections (UTIs). About 90 women with a history of repeat UTIs will take either a probiotic or a placebo (a dummy pill) for 6 months. The goal is to see if the probiotic…

This study looks at whether a special team of doctors and nurses can treat adults with suspected infections at home, instead of sending them to the hospital. About 500 people will be randomly assigned to either standard hospital care or home-based care from a mobile response team…

This study aimed to see if taking antibiotics for three days after a type of prostate surgery (HoLEP) lowers the chance of getting a urinary tract infection. It was designed for men over 40 with an enlarged prostate and no current infection. However, the study was withdrawn befor…

This study tests whether giving menstrual cups to economically vulnerable women in Kenya can lower rates of bacterial vaginosis (BV) and sexually transmitted infections (STIs). The cup is a reusable silicone device that collects menstrual blood and can be worn during sex. Researc…

This study tests a new way to treat viral infections that often occur after a solid organ transplant. Researchers create special immune cells, called viral-specific T-cells, from the patient's own blood to fight the virus. The goal is to reduce the need for strong anti-viral drug…

This study tests whether giving probiotics (Bacillus clausii) to critically ill adults can reduce serious infections like pneumonia and bloodstream infections. One hundred ICU patients will receive either the probiotic or a sugar pill, and researchers will track infection rates a…

This study tests a bladder stimulation technique (gentle lower back massage and lower abdomen tapping) to collect urine from infants under 6 months in the emergency department. The goal is to see if this method gets cleaner samples faster than the usual adhesive bag. 124 infants …

This study evaluates a new test called the QIAstat-Dx cUTI Plus AMR Panel, which aims to quickly detect bacteria and antibiotic resistance in urine samples from people with suspected complicated urinary tract infections (cUTI). Researchers will enroll 1500 participants of all age…

This study tests whether using a chlorhexidine rinse after bowel movements can reduce urinary tract infections (UTIs) in post-menopausal women who already use vaginal estrogen and have frequent UTIs. About 136 women aged 55-89 will be randomly assigned to use either the chlorhexi…

This study looks at two forms of vaginal estrogen—cream and tablet—to see which one post-menopausal women prefer for preventing recurrent urinary tract infections (UTIs). About 21 women who have had multiple UTIs will try both treatments and then choose their favorite. The goal i…

This study explores why cranberries prevent urinary tract infections (UTIs) in some women but not others. Researchers will test the urine of 55 healthy women before and after drinking cranberry juice to see if it stops bacteria from sticking to the bladder. The goal is to identif…

This study compares cranberry tablets to the antibiotic nitrofurantoin for preventing urinary tract infections (UTIs) in women after pelvic organ prolapse or incontinence surgery. About 142 women will be randomly assigned to take either cranberry capsules or nitrofurantoin for a …

This study tests whether education from a nurse – either in person or through tele-nursing (like WhatsApp) – can help people with multiple sclerosis feel less tired, have less pain, sleep better, and get fewer urinary tract infections. About 96 adults with relapsing-remitting MS …

This study looks at 300 pregnant women who have an epidural during labor. It compares leaving a catheter in place all the time versus inserting and removing it every few hours. The goal is to see which method leads to fewer bladder issues and infections after giving birth.

This study follows 28 kidney transplant recipients who are switching from one anti-rejection drug (anticalcineurin) to another (belatacept). Researchers want to see how this change affects the immune system's ability to fight the common CMV virus. Participants will have blood tes…

This study is creating a large registry of 600 adults who use catheters to empty their bladder due to nerve damage or other causes. Participants will report on their satisfaction, quality of life, and any infections or complications. The goal is to gather real-world data to bette…

This study aimed to help 4th graders develop healthy bladder habits by providing education, water stations, and changes to classroom bathroom policies. Researchers planned to track bathroom use, symptom scores, and urine volume. However, the study was withdrawn before enrolling a…

This study planned to compare how often women get urinary tract infections after giving birth, depending on whether they had a catheter during labour. It aimed to include pregnant women at 37 weeks or more. However, the study was withdrawn before enrolling any participants, so no…

This study reviews medical records of 50 adults who received a simultaneous liver-kidney transplant between 2015 and 2020. Researchers want to find out how many of them developed BK virus in their blood, which can harm the new kidney. The goal is to better understand this risk in…

This study follows 500 people with urinary tract infections (UTIs) for up to 5 years. Researchers will collect health, lifestyle, and lab data to learn which treatments work best and how to reduce antibiotic resistance. The goal is to improve patient care and guide future studies…

This study aimed to see if a computer could learn to predict how long a patient would stay in a home hospital program. Researchers planned to use data from past patients to train the computer. However, the study was withdrawn before any patients were enrolled, so no results are a…

This study uses interviews and focus groups to understand how transcutaneous tibial nerve stimulation (TTNS) impacts quality of life and daily activities in 75 people with neurogenic bladder from spinal cord injuries. Researchers aim to identify key themes about bladder function …

This study tests whether a hospital-customized plan (ROAD Home) reduces unnecessary antibiotic use at discharge for adults with pneumonia or urinary tract infections. Forty hospitals are randomly assigned to either use this tailored approach or continue their usual practices. The…

This study tests whether using rapid, advanced lab tests to identify the exact bacteria causing a severe infection can help doctors choose the right antibiotics faster. About 190 adults with sepsis in Greek ICUs will either get standard care or the new testing strategy. The goal …

This study tests a 'discharge stewardship bundle' to help doctors prescribe the right antibiotics for the right duration when children leave the hospital. Over 1,100 children with pneumonia, urinary tract infections, or skin infections will be followed. Doctors receive feedback r…

This study is testing whether a simple urine test can detect signs of kidney transplant rejection in children. Researchers are looking for specific molecules in urine that signal the body is attacking the new kidney. If the test works, it could help doctors spot problems early wi…

This study aims to find blood biomarkers that predict recurrent urinary tract infections (UTIs) in women. Researchers will collect blood, urine, fecal, and vaginal samples from 109 healthy women aged 18–28, comparing those with a history of single versus recurrent cystitis. The g…

This study looks at immune cells from people with autoimmune diseases (like lupus), people with infections, and healthy volunteers. Researchers want to understand how these cells differ and what makes them attack the body in autoimmune conditions. The study involves blood and bon…