Temporomandibular joint dysfunction syndrome

This study tests whether a new Fast Fix suturing system works better than the usual method for repositioning the jaw joint disc in people with TMJ internal derangement. About 50 adults who need surgery after other treatments failed will be randomly assigned to one of the two tech…

This study will test a 4D virtual simulator called Modjaw to see if it helps doctors diagnose temporomandibular joint (TMJ) disorders more accurately. About 20 adults with suspected disc displacement will use the device, and the results will be compared to MRI scans. The goal is …

This trial tests whether a new type of dental splint—made with both hard and soft 3D-printed materials—can improve comfort and outcomes for people with temporomandibular joint (TMJ) disorders. It compares the hybrid splint to conventional chairside splints and standard 3D-printed…

This study tests whether applying local heat to the jaw can reduce pain and fatigue caused by teeth clenching in people with chronic temporomandibular disorder (TMD). Ten adults with TMD will receive heat therapy and report their pain levels daily for 8 days. Researchers will com…

This trial tests whether washing out the jaw joint (arthrocentesis) works as well as Botox injections for treating painful temporomandibular joint (TMJ) disorders. Adults with TMJ pain that hasn't improved with standard care will be randomly assigned to one of the two procedures.…

This study tests whether adding a gentle muscle-release technique called Strain Counter-Strain to standard Rocabado exercises provides better relief for people with temporomandibular joint (TMJ) dysfunction. The trial includes 44 adults aged 20 to 50 with mild to moderate TMJ pai…

This study tests whether shining specific light wavelengths (635, 940, or 1064 nm) on the jaw muscles can reduce pain and improve jaw function in people with chronic jaw muscle disorder (TMD). About 45 adults with moderate-to-severe jaw pain lasting over 3 months will receive sev…

This study looks at two treatments for a jaw joint condition called disc displacement without reduction, which causes pain and trouble opening the mouth. Fifty-two adults who haven't gotten better with standard care will be randomly assigned to get either arthroscopic surgery alo…

This study tests which injection mixture works better for people with a displaced jaw joint (TMJ) that still clicks and moves. Twenty adults will receive either a mix of hyaluronic acid and steroids or hyaluronic acid and platelet-rich plasma after a joint washout. The goal is to…

This study tests whether adding dual-task exercises (combining physical movements with mental tasks) to standard physiotherapy, delivered via telerehabilitation, can reduce pain and improve jaw function in young adults with temporomandibular joint (TMJ) dysfunction. Thirty partic…

This study tests two methods of injecting platelet-rich fibrin (PRF) into the jaw joint for people with a displaced disc that causes pain and limited mouth opening. One method uses ultrasound to guide the needle, the other uses a tiny camera (arthroscope). The goal is to see whic…

This study tests whether taking tranexamic acid pills for a week after knee replacement surgery helps people recover better. 350 adults having their first knee replacement will receive either the drug or a placebo. Researchers will track pain, stiffness, and function for up to 2 …

This study tests whether combining physiotherapy, structured exercise, and psychological support can reduce the burden of chronic tinnitus (ringing in the ears) in 160 adults aged 18-70. Participants will be randomly assigned to either the 8-week multimodal program or a control g…

This study tests whether a mix of two drugs (triamcinolone and lidocaine) injected into jaw muscle trigger points can reduce pain in people with TMJ disorders. About 30 adults will receive either the active injection or a placebo. The main goal is to see if it lowers pain intensi…

This study compares two methods of injecting medicine into the jaw joint to relieve pain and improve function: one using a tiny camera (arthroscopy) and the other using ultrasound guidance. About 50 adults with long-term jaw pain will take part. The goal is to see which approach …

This study tests whether adding core-strengthening exercises to standard physical therapy can reduce pain and improve function in people with temporomandibular joint (TMJ) disorders. Fifty adults with jaw pain will be randomly assigned to either standard TMJ therapy or standard t…

This study is translating and testing an Italian version of a questionnaire that measures kinesiophobia—the fear of movement—in people with temporomandibular disorders (TMDs), which affect the jaw joint and muscles. Researchers will ask 250 adults diagnosed with TMD to complete t…

This study looks at how a procedure called temporomandibular joint arthrocentesis—a washout of the jaw joint—affects the masseter muscle, a key chewing muscle. Researchers will use ultrasound and strain elastography to measure the muscle's thickness and elasticity before and afte…

This study looks at whether the way your jaw and teeth fit together (called malocclusion) is related to your body posture. Researchers will use a 3D scanner to measure the spine's curves and alignment in people with different types of jaw misalignment. The goal is to better under…

This study looks at 700 adults who had jaw joint (TMJ) surgery and received either platelet-rich plasma (PRP) or platelet-rich fibrin (PRF) injections during the operation. Researchers will review medical records to see which group had less pain and better jaw function six months…

This observational study in Mexico will follow 30 adults already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans of the knees, CT scans of the heart, and body composition tests to see how the drug affects cartilage, heart fat, and overal…

This study looks at whether a specially trained physical therapist can diagnose jaw disorders (like TMJ) as accurately as an oral surgeon. 70 people with jaw pain will be checked by both a physical therapist and a surgeon, and their diagnoses will be compared. The goal is to see …

This study will observe 300 people with long-term jaw and face muscle pain (TMD) to see how psychological factors relate to their physical symptoms. Participants will fill out questionnaires about their pain and other body symptoms. The goal is to better understand the role of me…

This observational study will measure how well the upper neck moves and how that relates to jaw motion in 50 adults with temporomandibular disorders (TMD). Participants will have their neck and jaw movements measured with simple tools. The goal is to understand if limited neck mo…

This study looks at how the position of your head affects the movement of your jaw joints (TMJ) in people aged 11 to 65 who are getting braces or dental reconstruction. Researchers will measure jaw and neck movement before and after a brief hands-on therapy session to see if it h…