Could a simple pill boost knee replacement recovery?

NCT ID NCT07494032

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether taking tranexamic acid pills for a week after knee replacement surgery helps people recover better. 350 adults having their first knee replacement will receive either the drug or a placebo. Researchers will track pain, stiffness, and function for up to 2 years to see if the drug makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
tranexamic acid
What this could lead to
If it works, this could mean a simple, cheap pill after knee replacement leads to better pain relief and faster recovery.
What could go wrong
This is a small, early-stage trial. The drug may not improve outcomes more than placebo, and side effects like blood clots are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for KNEE ARTHROPATHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NYU Langone Health

    New York, New York, 10016, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.