Refractive error

This study tests a new ultraviolet femtosecond laser for creating corneal flaps during LASIK surgery to correct refractive errors. About 128 participants in Australia will receive LASIK using either the new UV laser or an existing infrared laser. The main goal is to check how saf…

This trial evaluates whether REVIVE toric soft contact lenses can effectively correct vision in adults with astigmatism. Participants wear the lenses daily for about a week, and researchers measure visual acuity at a follow-up visit. The study aims to assess the lenses' performan…

This completed study tested how well delefilcon A contact lenses with different diameters and base curves fit the eyes of 257 people with nearsightedness. Researchers checked lens movement and centration right after insertion and again after 6 hours. The goal was to find which le…

This trial tests whether providing free reading glasses to textile workers aged 35 and older with presbyopia (age-related difficulty seeing close up) can improve their work productivity. Workers at a garment factory in India will be randomly assigned to receive glasses or not, an…

This trial tests whether providing free reading glasses to textile workers aged 30 and older with presbyopia (age-related difficulty seeing close up) helps them stay employed longer. Over 1,200 workers in India will either receive glasses or not, and researchers will track how ma…

This trial is testing whether a new daily disposable contact lens, PEGAVISION G3, is as safe and effective as an existing lens (Clariti 1 day) for correcting nearsightedness. Adults with mild to moderate myopia will wear the lenses for three months, and researchers will measure v…

This study tests whether progressive addition lenses (PALs), like bifocals without a visible line, can slow the progression of low myopia (nearsightedness) in children who have certain focusing traits. About 118 children with low myopia and specific vision characteristics were ra…

This trial tests two different contact lenses designed to slow down the progression of myopia (nearsightedness) in children aged 6 to 11. Each child wears one type of lens on each eye for six months, then switches, so researchers can compare how well each lens controls eye growth…

This study tested two types of advanced glasses—lenslet spectacles and violet filter glasses—against standard single-vision lenses to see if they could slow the worsening of nearsightedness (myopia) in 90 people aged 8 to 20. Participants wore the glasses during all waking hours …

This study looked at whether adding bifocal glasses to daily atropine eye drops works better than atropine alone to slow down nearsightedness (myopia) in children. 210 kids aged 4-16 with worsening myopia took part. The main goal was to measure changes in their vision prescriptio…

This phase 3 study tested the long-term safety of LNZ101 eye drops, a combination of aceclidine and brimonidine, in 362 adults aged 45-75 with presbyopia (age-related blurry near vision). Participants used the drops regularly and were monitored for side effects. The study is comp…

This study tested a special laser (femtosecond laser) to adjust an artificial lens already placed inside the eye after cataract surgery. The goal was to correct leftover blurriness or astigmatism so people need glasses less. Twelve adults with at least one diopter of remaining re…

This study tested whether orthokeratology (OK) lenses, worn overnight, can slow the progression of nearsightedness (myopia) in children aged 8 to 15. The lenses reshape the cornea to change how light focuses on the retina. Researchers measured changes in eye length and retinal fo…

This study tested whether a low-intensity red light device could slow the worsening of nearsightedness (myopia) in children aged 8 to 12. Forty children participated, with some using the red light treatment for 3 months while others did not. The main goal was to see if the treatm…

This study tested a new silicone hydrogel contact lens (MSiHy) for correcting nearsightedness. 134 adults who already wore contacts were randomly assigned to try either the new lens or a standard monthly lens. The goal was to see if the new lens provides clear vision and is safe …

Researchers in Denmark are screening teenagers with Down syndrome for keratoconus, a condition that thins and bulges the cornea and can blur vision. The study uses corneal tomography to measure how common keratoconus is at different ages in this group. The goal is to find the bes…

This study tested two new devices that automatically measure vision in children aged 6 to 16. The devices use special lenses that adjust themselves, avoiding the need for eye drops that dilate the pupils. Researchers compared the results from 43 children to the standard dilation …

This study tested a new prototype device that uses light field technology to measure vision problems like nearsightedness and farsightedness. Researchers compared its accuracy to standard methods in 120 healthy adults. The goal was to see if this new approach could reliably deter…

This trial tests whether wavefront-guided LASIK, set to create monovision in one eye for near vision and the other for distance, can improve vision and reduce the need for reading glasses in people with presbyopia. About 219 participants aged 40 and older with mild to moderate ne…

This study tested whether glasses made with a new prescription method (Essilor AVA) give better vision and comfort than standard glasses. About 120 adults with common vision problems wore both types of lenses for two weeks each. The goal was to see which people preferred and if t…

This study tested an eye drop called LNZ101 to help people with presbyopia (age-related trouble seeing up close) read without glasses. 469 adults aged 45-75 received the drops, and researchers measured how many gained clear near vision without losing distance vision on the first …

This study tested two types of soft contact lenses—Proclear 1 Day and MyDay sphere—to see which one feels more comfortable. 44 adults who already wear contact lenses rated comfort on a scale from 0 to 100. The goal was simply to compare the lenses, not to treat or cure any eye di…

This study looked at 40 people over 45 who had cataract surgery with a special lens that helps with both near and far vision. Half of them had the surgery with digital assistance, and half without. The goal was to see if the digital help led to better vision or more satisfaction …

This Phase 3 trial tested LNZ101 eye drops in 229 people aged 45-75 with presbyopia, a condition that makes it hard to see up close. The drops combine aceclidine and brimonidine to temporarily improve near vision. The main goal was to see if participants could read three lines be…

This completed study tested a new daily disposable contact lens called DSiHy for correcting nearsightedness (myopia). 134 adults who already wore contacts were randomly assigned to use either the new lens or a standard daily lens. The goal was to see if the new lens provides clea…

This study tested whether a program of eye exercises could improve visual function and quality of life in 40 adults with refractive errors like nearsightedness, farsightedness, or astigmatism. Participants did 20-minute sessions three times a week for eight weeks, plus home exerc…

This study looks at whether taking combined oral contraceptive pills changes the shape and optical quality of the cornea — the clear front part of the eye. Researchers will measure corneal curvature and irregularities in women aged 18-40 before they start the pill and again after…

This study checked if a smartphone app called VisionApp can accurately measure vision problems like nearsightedness and presbyopia (age-related reading difficulty). Sixteen adults aged 40 and older used the app at home, and their results were compared to standard eye exams. The g…

This study looked at whether using eye drops to dilate (widen) the pupils before measuring vision leads to better eyeglass prescriptions for people with Down syndrome. 42 participants had their vision tested with and without dilation. The goal was to see which method gives sharpe…

This study tested four different approaches to find and treat eye diseases like cataracts, glaucoma, and diabetic retinopathy in communities in Nepal. Over 87,000 people aged 50 and older took part. The goal was to see which method—comprehensive screening, cataract camps, communi…

This study looked at data from 1100 people who had SMILE laser eye surgery to fix nearsightedness. Researchers used a computer model to predict how well patients would see one year after surgery. The goal was to see if the model could give more accurate results than the usual pla…

This study tested how well a new device (ELITA) docks onto the eye for refractive error treatment. 55 adults participated to see if the docking procedure works correctly. The study did not provide treatment, only measured the device's performance.

This study tested if sending SMS reminders to parents helps children get follow-up eye care after a school vision screening. About 320 children aged 5-15 from two schools in Rawalpindi, Pakistan, were screened using a smartphone app. Those who needed further care were split into …