Lung disorder
MONDO:0005275A disease involving the lung.
Also known as: disease of lung, disease or disorder of lung, disorder of lung, lung disease, lung disease or disorder, lung disorder, lung disorders, pulmonary disease
7091 clinical trials for this condition and its sub-types, 251 tagged with Lung disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Lung disorder
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Lung neoplasm 1,371 trials · 4,046 incl. sub-types
10 sub-types
- Lung cancer 1,212 trials · 3,948 incl. sub-types Sub-types →
- Lung neuroendocrine neoplasm 21 trials · 540 incl. sub-types Sub-types →
- Lung benign neoplasm 1 trial · 2 incl. sub-types Sub-types →
- Lung PEComa 0 trials · 1 incl. sub-types Sub-types →
- Pulmonary sulcus neoplasm 0 trials · 1 incl. sub-types Sub-types →
- Langerhans cell histiocytosis specific to adulthood 0 trials Sub-types →
- Fibroma of lung 0 trials
- Hamartoma of lung 0 trials Sub-types →
- Lung germ cell tumor 0 trials
- Lung hilum neoplasm 0 trials Sub-types →
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Obstructive lung disease 36 trials · 1,074 incl. sub-types
1 sub-type
- Chronic obstructive pulmonary disease 937 trials · 1,054 incl. sub-types Sub-types →
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Respiratory failure 280 trials · 790 incl. sub-types
2 sub-types
- Acute respiratory failure 153 trials · 588 incl. sub-types Sub-types →
- Respiratory paralysis 20 trials
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Interstitial lung disease 257 trials · 729 incl. sub-types
14 sub-types
- Idiopathic pulmonary fibrosis 202 trials
- Interstitial lung disease specific to childhood 5 trials · 163 incl. sub-types Sub-types →
- Pulmonary fibrosis 140 trials · 143 incl. sub-types Sub-types →
- Bronchiolitis obliterans syndrome 42 trials · 44 incl. sub-types Sub-types →
- Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types Sub-types →
- Secondary pulmonary hemosiderosis 0 trials · 30 incl. sub-types Sub-types →
- Interstitial lung disease specific to adulthood 0 trials · 20 incl. sub-types Sub-types →
- Radiation pneumonitis 20 trials
- Pneumoconiosis 5 trials · 13 incl. sub-types Sub-types →
- Inherited interstitial lung disease 5 trials · 11 incl. sub-types Sub-types →
- Drug or radiation exposure-related interstitial lung disease 2 trials
- Bronchiolocentric pattern of interstitial pneumonia 0 trials
- Isolated pulmonary capillaritis 0 trials
- Pulmonary fibrosis-hepatic hyperplasia-bone marrow hypoplasia syndrome 0 trials
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Pneumonitis 15 trials · 646 incl. sub-types
6 sub-types
- Pneumonia 327 trials · 611 incl. sub-types Sub-types →
- Hypersensitivity pneumonitis 25 trials · 30 incl. sub-types Sub-types →
- Radiation pneumonitis 20 trials
- Aspiration pneumonitis 2 trials Sub-types →
- Ichthyosis prematurity syndrome 1 trial
- Toxic pneumonitis 0 trials
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Bronchiolitis 51 trials · 104 incl. sub-types
6 sub-types
- Bronchiolitis obliterans syndrome 42 trials · 44 incl. sub-types Sub-types →
- Acute bronchiolitis 19 trials
- Respiratory syncytial virus bronchiolitis 6 trials
- Postinfectious bronchiolitis obliterans 2 trials
- Mac-Leod-Swyer-James-Syndrome 0 trials
- Toxic bronchiolitis 0 trials Sub-types →
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Acute lung injury 90 trials
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Fungal lung infectious disease 6 trials · 57 incl. sub-types
5 sub-types
- Pulmonary aspergilloma 11 trials · 38 incl. sub-types Sub-types →
- Pneumocystosis 19 trials
- Adiaspiromycosis 0 trials
- Cork-handlers' disease 0 trials
- Maple bark strippers' lung 0 trials
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Aspiration pneumonia 33 trials
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Acute chest syndrome 30 trials
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Middle lobe syndrome 29 trials
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Pulmonary systemic sclerosis 27 trials
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Pulmonary coin lesion 24 trials
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Pulmonary alveolar proteinosis 9 trials · 13 incl. sub-types
3 sub-types
- Autoimmune pulmonary alveolar proteinosis 6 trials
- Hereditary pulmonary alveolar proteinosis 3 trials · 6 incl. sub-types Sub-types →
- Secondary pulmonary alveolar proteinosis 0 trials
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Pulmonary artery disease 12 trials
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Restrictive pulmonary disease 8 trials
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Occupational lung disease 4 trials · 8 incl. sub-types
8 sub-types
- Occupational asthma 3 trials
- Bird fancier's lung 1 trial
- Bagassosis 0 trials
- Cork-handlers' disease 0 trials
- Farmer's lung disease 0 trials
- Malt worker's lung 0 trials
- Maple bark strippers' lung 0 trials
- Mushroom workers' lung 0 trials
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Neonatal aspiration syndrome 1 trial · 6 incl. sub-types
2 sub-types
- Meconium aspiration syndrome 5 trials
- Massive neonatal aspiration syndrome 0 trials
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Lung abscess 3 trials
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Pneumonic plague 3 trials
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Hantavirus pulmonary syndrome 2 trials
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Pulmonary immaturity 2 trials
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Wilson-Mikity syndrome 0 trials
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Dystrophic pulmonary ossification 0 trials
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Pulmonary alveolar microlithiasis 0 trials
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Pulmonary embolism and infarction 0 trials
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Pulmonary plasma cell granuloma 0 trials
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Pulmonary venoocclusive disease 0 trials
2 sub-types
- Pulmonary venoocclusive disease 1 0 trials
- Pulmonary venoocclusive disease 2 0 trials
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Shrinking lung syndrome 0 trials
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Silo filler disease 0 trials
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Vanishing lung syndrome 0 trials
Most studied deeper sub-types
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Placenta cells tested as COVID fighter – but trial stopped early
Disease control Stopped earlyThis early-phase trial tested a new therapy called CYNK-001, which uses natural killer cells from the placenta to fight COVID-19. It enrolled only 7 adults with moderate COVID-19. The study was terminated early, so we have limited information on safety and effectiveness.
Phase 1/2 • Sponsor: Celularity Incorporated • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Inhaled treprostinil safety trial for PH-COPD ends early
Disease control Stopped earlyThis study looked at the long-term safety of an inhaled drug called treprostinil in people who have both pulmonary hypertension (high blood pressure in the lungs) and COPD. It included 41 adults who had already completed a previous study. The trial was terminated early, and the m…
Phase 3 • Sponsor: United Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Targeted pill shows promise for rare lung cancer, but trial stopped early
Disease control Stopped earlyThis phase 3 study tested a new drug called pralsetinib against standard chemotherapy for people with a specific type of advanced lung cancer that has a RET gene fusion. The goal was to see if pralsetinib could better delay cancer growth. The trial was terminated early, so full r…
Phase 3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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New inhaled drug aimed at stubborn lung infection shows promise, but trial halted early
Disease control Stopped earlyThis phase 3 study tested an inhaled form of the antibiotic clofazimine added to standard therapy for people with MAC lung disease that did not respond to previous treatment. The goal was to see if the drug could clear the infection from sputum cultures and improve quality of lif…
Phase 3 • Sponsor: Mannkind Corporation • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Experimental asthma drug briquilimab fails to reach Late-Stage testing
Disease control Stopped earlyThis Phase 1 trial tested a single dose of briquilimab in 17 adults with mild-to-moderate allergic asthma to see if it was safe and could reduce asthma attacks triggered by allergens. The study was terminated early, meaning it did not continue as planned. The main goal was to che…
Phase 1 • Sponsor: Jasper Therapeutics, Inc. • Aim: Disease control
Last updated Jun 26, 2026 18:40 UTC
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New screening tool could uncover thousands of undiagnosed lung cases
Diagnosis Stopped earlyThis study tested a French version of the CAPTURE tool, which uses a short questionnaire and a peak flow breath test, to find people with undiagnosed obstructive lung disease (like COPD). Over 1,000 adults aged 40 and older who had not been diagnosed with asthma or COPD took part…
Sponsor: Groupe Hospitalier du Havre • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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Chilly wash may stop biopsy bleeding
Symptom relief Stopped earlyThis study tested whether rinsing the lung with cold salt water before a biopsy could reduce bleeding and make slides easier to read. Only 6 adults having a lung ultrasound and biopsy took part. The study was stopped early, so results are limited.
Sponsor: TriHealth Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Microscope inside the lungs reveals hidden damage in two diseases
Knowledge-focused Stopped earlyThis study used a special microscope on the tip of a thin tube (bronchoscope) to look at the smallest blood vessels in the lungs of people with scleroderma or emphysema. The goal was to see how these vessels change in each disease. Only 9 patients were enrolled before the study w…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Scientists investigate why ventilators may worsen lung infections
Knowledge-focused Stopped earlyThis study looked at how mechanical ventilation (breathing machines) affects the energy centers (mitochondria) of immune cells in patients with severe lung infections and acute respiratory distress syndrome (ARDS). Researchers aimed to understand why some patients get worse despi…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC