Injury

Researchers test whether using a minimally invasive heart monitor during surgery can reduce complications in severely injured trauma patients. The monitor, called FloTrac with the EV1000 platform, tracks blood flow and heart function continuously. Doctors use its readings to guid…

This trial tests whether valproate, a medication used for epilepsy, can help prevent or ease alcohol withdrawal symptoms in heavy drinkers admitted to trauma care. Participants receive standard treatment with lorazepam (a benzodiazepine) as needed, and some also get valproate. Th…

This study tested a dramatic approach: rapidly cooling trauma patients whose hearts had stopped from severe bleeding. Doctors flushed ice-cold saline into the aorta to induce deep hypothermia, then performed emergency surgery to stop the bleeding before slowly rewarming the patie…

This study tested whether applying 0.25% timolol gel (a beta-blocker eye drop used for glaucoma) to skin grafts could improve healing and appearance after skin cancer surgery. Researchers planned to enroll 82 patients but stopped early with only 10 participants. The goal was to s…

This study aimed to see if the steroid dexamethasone could help people with traumatic brain injury who had brain contusions and swelling. It planned to enroll 600 adults, giving them a short course of dexamethasone or a placebo. The main goal was to measure recovery using the Gla…

This study tested a drug called VS-01 for people with severe confusion caused by liver disease (overt hepatic encephalopathy). The trial planned to enroll many participants but was stopped early after only 3 people joined. Researchers wanted to see if VS-01 could help patients re…

This study tested a single dose of a drug called BE1116 (a 4-factor prothrombin complex concentrate) in people with traumatic injuries and severe bleeding. The goal was to see if it could improve survival within 6 hours compared to a placebo. The trial was stopped early after enr…

This study tested lithium disilicate crowns made with CAD/CAM technology in 8 adults with cavities or damaged teeth. The crowns were placed using different adhesive methods to check for sensitivity and quality. The trial was terminated early, so the findings are limited.

This pilot study tested whether a new imaging technique called shear-wave elastography (SWE) combined with MRI can detect radiation-induced injury to the uterus. Researchers recruited women who had pelvic radiation before age 40 and compared their scans to healthy controls. The g…

This study tested whether a silicone adhesive dressing called Embrace can improve the look of scars after skin surgery. Half of each surgical wound was treated with the device, the other half with standard care. The trial was stopped early, so results are limited, but the goal wa…

This pilot study tested a 24-hour IV infusion of brexanolone in 10 adult women with PTSD from non-military trauma. The goal was to see if it could reduce PTSD symptoms and lead to remission by 12 weeks. The trial was terminated early, so results are limited.

This study tested a new type of wound vacuum dressing on 7 people with chronic or acute wounds. The goal was to see if the dressing helps wounds heal or get better. The study was stopped early, so results are limited.

This clinical trial is testing a device that has not been approved or cleared by the U.S. FDA. The purpose is to learn more about how the device works and its effects on participants. Because key details are not publicly available, the exact goals and methods are unclear.

This study uses MRI and ultrasound to map where hamstring muscle injuries occur in recreational to professional athletes. By linking injury location with how the injury happened, researchers aim to better understand these common sports injuries. The goal is to improve prevention …

This study tested a camera that detects natural glow (autofluorescence) from skin wounds and surrounding tissue. Researchers planned to catalog these glow patterns from 50 people with acute or chronic wounds, but the study was stopped early after only 11 participants. Because it …

This study tested three portable inhaler devices in 10 healthy adults to see how accurately they measure airflow and record breaths. No medication was used—only a harmless salt solution. The goal was to compare device performance and user comfort, not to treat any disease.

This study looked at the VERTICALE Cervical System, a device used to stabilize the spine during surgery. Researchers planned to track neck disability in patients with conditions like degenerative disc disease or trauma. Only 4 patients were enrolled before the study was terminate…

This study looked at whether dissolvable stitches (chromic gut) or non-dissolvable stitches (nylon) work better for hand and forearm cuts treated in the emergency room. Six adults with such cuts were followed for 12 weeks to compare scar healing and pain. The goal was to see whic…

This study aimed to understand how and when injuries happen during CrossFit training. Over 500 participants from Reunion Island filled out questionnaires about their injuries for up to 12 months. The goal was to identify injury locations, causes, and patterns to help make the spo…

This study aimed to collect movement data from healthy teens aged 13-25 who play land-based sports. Researchers wanted to create a baseline of normal movement patterns to compare with injured athletes. The study was terminated early and enrolled only 14 of the planned 40 particip…

This study tested new GentleFit non-invasive ventilation masks and prongs in children up to 3 years old. Researchers compared how well these interfaces delivered air pressure and monitored skin health over 24 hours. The goal was to see if the new designs fit better and work as we…

This study tested a group wellness program for women living in an emergency shelter after experiencing intimate partner violence. The program included mindfulness and health activities to improve physical and emotional well-being. Only 10 women took part, and the study was stoppe…

This study aimed to collect eye scans from people who had COVID-19 to see if the virus caused damage to the retina, the light-sensitive tissue at the back of the eye. Researchers planned to compare severe and mild COVID-19 cases, but the study was stopped early and only enrolled …