Liver drug trial halted after just 3 patients

NCT ID NCT06987968

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called VS-01 for people with severe confusion caused by liver disease (overt hepatic encephalopathy). The trial planned to enroll many participants but was stopped early after only 3 people joined. Researchers wanted to see if VS-01 could help patients recover faster when added to standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VS-01

What this could lead to

If it works, this could point toward a new treatment for severe liver-related confusion (hepatic encephalopathy).

What could go wrong

The trial was terminated early with only 3 participants, so there is very little data. It is unclear if VS-01 is safe or effective.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute-On-Chronic Liver Failure chronic liver failure cirrhosis of liver Fibrosis hepatic encephalopathy injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 96 Jonathan Lucas St, CSB (Main Hospital), Suite 908

    Charleston, South Carolina, 29425, United States

  • Georgian Clinics" Kutaisi Referral Hospital 2, Otskheli str.

    Kutaisi, 4600, Georgia

  • LEPL The First University Clinic of Tbilisi State, Medical University, Gudamakari str.4,,LEPL The First University Clinic

    Tbilisi, 0141, Georgia

  • LLC Geo Hospitals Tbilisi, Multiprofile Medical Center, Tsinandali ,str. 9/3

    Tbilisi, 0144, Georgia

  • Nouvel Hôpital Civil, Service de Medecine Intensive Reanimation, 1, place de l'Hôpital

    Strasbourg, 67091, France

  • Tbilisi State Medical University and Ingorokva, High Medical Technology University Clinic, Tsinandali Street

    Tbilisi, 0144, Georgia