Liver drug trial halted after just 3 patients

NCT ID NCT06987968

Terminated Disease control Sponsor: Genfit Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called VS-01 for people with severe confusion caused by liver disease (overt hepatic encephalopathy). The trial planned to enroll many participants but was stopped early after only 3 people joined. Researchers wanted to see if VS-01 could help patients recover faster when added to standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: VS-01
What this could lead to: If it works, this could point toward a new treatment for severe liver-related confusion (hepatic encephalopathy).
What could go wrong: The trial was terminated early with only 3 participants, so there is very little data. It is unclear if VS-01 is safe or effective.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acute-On-Chronic Liver Failure chronic liver failure cirrhosis of liver Fibrosis hepatic encephalopathy injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE-ON-CHRONIC LIVER FAILURE (ACLF) DECOMPENSATED CIRRHOSIS HEPATIC ENCEPHALOPATHY

Contacts and locations

Locations

96 Jonathan Lucas St, CSB (Main Hospital), Suite 908

Charleston, South Carolina, 29425, United States
Georgian Clinics" Kutaisi Referral Hospital 2, Otskheli str.

Kutaisi, 4600, Georgia
LEPL The First University Clinic of Tbilisi State, Medical University, Gudamakari str.4,,LEPL The First University Clinic

Tbilisi, 0141, Georgia
LLC Geo Hospitals Tbilisi, Multiprofile Medical Center, Tsinandali ,str. 9/3

Tbilisi, 0144, Georgia
Nouvel Hôpital Civil, Service de Medecine Intensive Reanimation, 1, place de l'Hôpital

Strasbourg, 67091, France
Tbilisi State Medical University and Ingorokva, High Medical Technology University Clinic, Tsinandali Street

Tbilisi, 0144, Georgia

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