New scan could reveal hidden uterine injury after cancer radiation

NCT ID NCT06518174

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study tested whether a new imaging technique called shear-wave elastography (SWE) combined with MRI can detect radiation-induced injury to the uterus. Researchers recruited women who had pelvic radiation before age 40 and compared their scans to healthy controls. The goal was to see if these scans could reliably measure uterine fibrosis and other damage.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
MRI, SWE, and US evaluation
What this could lead to
If successful, this imaging approach could help doctors identify uterine damage from radiation, potentially guiding future fertility-preserving treatments.
What could go wrong
This is a very small, early pilot study (only 8 participants) that was terminated, so results may be limited and not generalizable. The imaging techniques are still experimental for this use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Colorado

    Aurora, Colorado, 80045, United States