Steroid trial for brain injury halted early

NCT ID NCT04303065

Terminated Disease control Sponsor: Jon Pérez Bárcena Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to see if the steroid dexamethasone could help people with traumatic brain injury who had brain contusions and swelling. It planned to enroll 600 adults, giving them a short course of dexamethasone or a placebo. The main goal was to measure recovery using the Glasgow Outcome Scale at one and six months. However, the trial was terminated early, so no conclusions could be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexamethasone (a steroid anti-inflammatory drug)
What this could lead to: If it had succeeded, this could have pointed toward a treatment to reduce brain swelling and improve recovery after head injury.
What could go wrong: The trial was terminated, so results are not available. Steroids can have side effects like infection risk, and earlier studies have shown mixed results for brain injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CEREBRAL EDEMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

brain edema Brain Injuries, Traumatic Contusions Edema head injury injury traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL EDEMA HEAD INJURY TRAUMA TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

Hospital Universitari Son Espases

Palma de Mallorca, Balearic Islands, 07120, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.