Idiopathic hypersomnia
MONDO:0018044Idiopathic hypersomnia is a sleep disorder classified in two forms: idiopathic hypersomnia with long sleep time and idiopathic hypersomnia without long sleep time.
Also known as: primary hypersomnia, idiopathic hypersomnolence
40 clinical trials for this condition and its sub-types.
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Broader categories
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Pitolisant shows promise for Long-Term control of idiopathic hypersomnia
Disease control CompletedThis study looks at the long-term safety and effectiveness of pitolisant in adults with idiopathic hypersomnia, a condition causing excessive daytime sleepiness. Participants had already completed a previous study. The goal is to see if pitolisant remains safe and helps control s…
Phase: PHASE3 • Sponsor: Harmony Biosciences Management, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could a headband replace the sleep lab? new study tests At-Home narcolepsy diagnosis
Diagnosis CompletedThis study tested a headband called Dreem 3S that people wear at home to monitor sleep and wake patterns. The goal was to see if it can help diagnose narcolepsy, a condition that causes extreme daytime sleepiness. 78 adults took part, and researchers checked how well the device w…
Sponsor: Beacon Biosignals • Aim: Diagnosis
Last updated Jun 27, 2026 11:03 UTC
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Could a new pill help people who feel sleepy all day?
Symptom relief CompletedThis study tests an oral drug called SDX (serdexmethylphenidate) to see if it safely reduces excessive daytime sleepiness in adults with idiopathic hypersomnia, a condition where people feel extremely sleepy during the day despite getting enough sleep at night. Participants will …
Phase: PHASE2 • Sponsor: Zevra Therapeutics • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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New nightly pill aims to tame daytime sleepiness in rare sleep disorder
Symptom relief CompletedThis study tested a once-nightly extended-release form of sodium oxybate (FT218) in 157 adults with idiopathic hypersomnia, a condition causing excessive daytime sleepiness despite adequate sleep. Participants were already on stable doses of stimulants or other alerting agents. T…
Phase: PHASE3 • Sponsor: Avadel • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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New sleep supplement tested in 60 adults – results pending
Symptom relief CompletedThis study tested a dietary supplement called Speed Sleep in 60 adults aged 18-65 who have trouble sleeping. Participants took either the supplement or a placebo daily for 4 weeks. Sleep quality and quantity were measured using Fitbit trackers and questionnaires.
Phase: NA • Sponsor: Bio Nature Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Herbal sleep aid shows promise in midlife insomnia trial
Symptom relief CompletedThis study tested whether a daily mix of plant protein and two herbs (ashwagandha and rhodiola) could improve sleep in 100 adults aged 35-70 with sleep troubles. Participants took either the supplement or a placebo for 30 days and reported their sleep quality daily. The goal was …
Phase: NA • Sponsor: Universidad Pablo de Olavide • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Sleep aid boosts immunity in small trial
Symptom relief CompletedThis early study tested a product called Chenghuang Circadian Rhythm Regulator in 15 adults with ongoing sleep problems. The goal was to see if it could improve sleep quality and immune markers. Results are not yet reported, but the study was small and had no comparison group.
Phase: NA • Sponsor: Shanghai Cell Therapy Group Co.,Ltd • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Headband that reads your brain waves may ease insomnia in menopausal women
Symptom relief CompletedThis study tested whether a headband called Muse-S, which senses brain activity, could help midlife women with sleep problems like insomnia. Thirty-one women going through menopause wore the device at home. The goal was to see if it was practical and if it improved sleep quality …
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 08:14 UTC
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Gentle pressure, deep sleep: acupressure shows promise for elderly insomnia
Symptom relief CompletedThis study tested whether acupressure—a gentle finger-pressure technique on specific body points—could improve sleep in elderly people living in care homes. 75 residents took part, with half receiving 12 acupressure sessions over four weeks. The results showed that those who rece…
Phase: NA • Sponsor: Duzce University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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New online course helps seniors kick the benzo habit
Symptom relief CompletedThis study tested an online program called ALDER that teaches older adults skills to boost positive emotions and reduce anxiety. 33 people aged 65 and older who used benzodiazepines (anti-anxiety or sleep medications) at least twice a week took part. Over 5 weeks, they learned an…
Phase: NA • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Better sleep could ease severe mental illness symptoms, study finds
Symptom relief CompletedThis study tested a sleep and circadian treatment (TranS-C) for people with severe mental illness (SMI) in community mental health centers. The treatment was adapted to better fit these settings. Researchers looked at whether it improved sleep, daily functioning, and symptoms in …
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Better sleep, better mental health: new training approach tested in community clinics
Symptom relief CompletedThis study tested two versions of a sleep treatment for people with severe mental illness in community mental health centers. One version was the standard treatment, and the other was adapted to better fit patients' needs. The goal was to see if training clinic staff to deliver t…
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Smart system aims to crack brain disorder diagnosis
Knowledge-focused CompletedThis study tested a computer system designed to help doctors more accurately diagnose and manage complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected health data from 635 people visiting specialty clinics, including healthy volunteers, to see…
Sponsor: Neurological Institute of Athens • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New website aims to boost social skills for teens with narcolepsy
Knowledge-focused CompletedThis study tested a website designed to help teenagers with narcolepsy or idiopathic hypersomnia and their families understand and improve social relationships. Twenty-five teens and their parents reviewed the website's content, which included animations, patient stories, and exp…
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Power nap or power play? study tests nap length on soccer agility
Knowledge-focused CompletedThis study looked at whether a 25-minute or 45-minute nap helps teenage soccer players run faster and feel less tired. Sixteen male players tried both nap lengths and a no-nap day. Results showed that napping improved agility and made exercise feel easier, but did not help them k…
Phase: NA • Sponsor: Uludag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC