Hypoglycemia

This study compares a lower dose of insulin (5 units) plus dextrose to the standard dose (10 units) for treating mild to moderate high potassium in emergency patients. Researchers want to see if the lower dose works just as well while causing fewer side effects like low blood sug…

This study tests whether an oral liquid form of glibenclamide can safely control high blood sugar in very premature infants (born before 32 weeks, weighing under 1.5 kg). The goal is to see if it can replace insulin injections. The trial involves 35 babies and monitors blood suga…

This study tests a program where community paramedics visit adults with diabetes who have had severe low blood sugar (hypoglycemia). The goal is to help them better manage their diabetes, prevent future emergencies, and improve their quality of life. About 150 participants from s…

This study tests a drug called avexitide in 75 adults who have dangerous low blood sugar episodes after gastric bypass surgery. Participants receive either the drug or a placebo for 16 weeks to see if it reduces severe sugar crashes. The goal is to control this long-term conditio…

This study tests whether using a continuous glucose monitor (CGM) helps dialysis patients with type 1 or type 2 diabetes control their blood sugar better than standard finger-prick tests. 96 participants will be split into three groups: standard care, intermittent CGM use, or con…

This study tests a device called the Cell Pouch, which is implanted in the abdomen to create a natural home for donor insulin-producing cells. The goal is to help people with type 1 diabetes who have dangerous low blood sugar episodes. Seventeen participants will receive the impl…

This study tests whether choosing diabetes medications based on a person's genetic profile helps control blood sugar better than standard treatment. About 500 adults with type 2 diabetes that is not well controlled will be randomly assigned to either gene-guided or standard care.…

This pilot study aimed to test whether a combination of four drugs—ATG, low-dose IL-2, adalimumab, and exenatide—could help people newly diagnosed with type 1 diabetes keep producing their own insulin. The trial planned to enroll adults aged 18-35 diagnosed within the last 120 da…

This study tests an investigational drug called RZ358 for people with congenital hyperinsulinism, a rare condition causing dangerously low blood sugar. The trial involves 56 participants aged 3 months to 45 years who still have low blood sugar despite standard treatments. Over 24…

This study tests a wireless glucose monitoring system (Glucose Telemetry System) in 218 hospitalized veterans with type 2 diabetes who are at high risk for low blood sugar (hypoglycemia). The device sends blood sugar readings from the patient's bedside to a monitor at the nursing…

This study tests whether transplanting insulin-producing islet cells from donors into the liver can help people with type 1 diabetes control blood sugar without insulin shots. Ten participants receive strong anti-rejection drugs to protect the new cells. Researchers will track bl…

This study tested a new treatment called SR-02, which involves implanting insulin-producing cells into the abdomen of adults with type 1 diabetes who experience dangerously low blood sugar. Participants would need to take lifelong anti-rejection drugs to prevent the body from att…

This study tests a drug called triheptanoin in 8 adults with MCADD, a rare condition that can cause dangerously low blood sugar. The goal is to see if the drug is safe and can prevent hypoglycemia during fasting. Participants will stay overnight at a hospital for monitoring and b…

This study aimed to see if a corn-starch based drink taken before exercise could lower the risk of delayed low blood sugar in teens with type 1 diabetes. It also looked at whether it could improve biking performance. The study was withdrawn before enrolling any participants, so n…

This study was designed to see if two drugs, empagliflozin and anakinra, could help people with prediabetes who experience low blood sugar after eating. The trial planned to give a single dose of each drug before a test meal and measure symptoms. However, the study was withdrawn …

This study checks if a Turkish version of a questionnaire about managing low blood sugar (hypoglycemia) is accurate and reliable. Researchers will ask 200 adults with type 2 diabetes who have had low blood sugar to fill out the questionnaire. The goal is to make sure the scale wo…

This study looks at how different doses of glucagon, a natural hormone that raises blood sugar, affect people who have low blood sugar after weight-loss surgery. Researchers will give 28 participants several doses of glucagon and measure their blood sugar and hormone levels. The …

This study aims to understand why some people without diabetes experience low blood sugar (hypoglycemia). Researchers will compare three groups: people with hypoglycemia who have had stomach surgery, those with hypoglycemia who haven't had surgery, and healthy controls. They will…

This study looks at 28 people who experience low blood sugar (hypoglycemia) after eating, often due to past stomach surgery. Researchers want to see if the types of bacteria in the gut are linked to how often and how severely blood sugar drops. Participants wear a continuous gluc…

This observational study looks at how often low blood sugar (hypoglycemia) occurs in children under 7 with Long QT syndrome who take the beta-blocker propranolol. Researchers will use a continuous glucose monitor for 10 days during healthy times and during an infection. They will…

This study looks at how low blood sugar (hypoglycemia) affects blood vessel function in people with type 2 diabetes and healthy adults. Researchers want to learn if a natural gut hormone called GLP-1 can change these effects. The study involves 28 participants and measures change…