Prediabetes low blood sugar trial pulled before it began

NCT ID NCT05174507

First seen Feb 22, 2026 · Last updated Jun 24, 2026 · Updated 19 times

Summary

This study planned to test whether empagliflozin or anakinra could reduce low blood sugar episodes after meals in people with prediabetes. Participants would have received a single dose of one drug or a placebo before a standardized meal. However, the trial was withdrawn before enrolling any participants, so no results are available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

empagliflozin and anakinra

What this could lead to

If it had worked, this could point toward a new way to treat low blood sugar after meals in people with prediabetes.

What could go wrong

The trial was withdrawn before enrolling anyone, so no data exist. Even if run, it was a small early-phase study with uncertain outcomes.

Conditions

The condition(s) this trial relates to.

hypoglycemia prediabetes syndrome type 1 diabetes mellitus 2

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.