New injection aims to stop dangerous blood sugar crashes after gastric bypass

NCT ID NCT06747468

Summary

This study is testing if a daily injection called avexitide can safely reduce episodes of dangerously low blood sugar in people who have had gastric bypass surgery. About 75 participants will receive either the real injection or a placebo (dummy shot) for 16 weeks, followed by a longer period where everyone gets the real treatment. The main goal is to see if the treatment lowers the number of severe low blood sugar events compared to the placebo.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Centricity Research Morehead City Multispecialty

    Morehead City, North Carolina, 28557-3126, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195-0001, United States

  • Consano Clinical Research

    Shavano Park, Texas, 78231-1281, United States

  • Cotton-O'Neil Diabetes and Endocrinology Center

    Topeka, Kansas, 66606-2806, United States

  • Diabetes and Gandular Disease Clinic

    San Antonio, Texas, 78229-4801, United States

  • Duke Center for Metabolic and Weight Loss Surgery

    Durham, North Carolina, 27704-2726, United States

  • East Coast Institute for Research

    Jacksonville, Florida, 32216, United States

  • Endocrine and Psychiatry Center

    Houston, Texas, 77095-2856, United States

  • Georgia Clincal Research

    Lawrenceville, Georgia, 30044, United States

  • Hanson Diabetes Center

    Port Charlotte, Florida, 33952-6722, United States

  • Joslin Diabetes Center

    Boston, Massachusetts, 02215-5306, United States

  • NYC Health + Hospitals/Queens - BRANY

    New Hyde Park, New York, 11042-1214, United States

  • Penn Medicine University City

    Philadelphia, Pennsylvania, 19104, United States

  • Southern Endocrinology & Diabetes Associates

    Mesquite, Texas, 75149, United States

  • Stanford Health Care - Endocrinology Clinic

    Stanford, California, 94304, United States

  • Texas Valley Clinical Research, LLC

    Weslaco, Texas, 78596-7288, United States

  • UT Health San Antonio

    San Antonio, Texas, 78229-3931, United States

  • UWHealth - Junction Rd Medical Center Endocrinology Clinic

    Madison, Wisconsin, 53717-2656, United States

  • University of Colorado Health Anschutz Medical Campus

    Aurora, Colorado, 80045-2541, United States

  • Vanderbilt Weight Loss Center

    Nashville, Tennessee, 37212-3609, United States

Conditions

Explore the condition pages connected to this study.