New hope for dangerous blood sugar drops after gastric bypass

NCT ID NCT06747468

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 26 times

Summary

This study tests a drug called avexitide in 75 adults who have severe low blood sugar episodes after gastric bypass surgery. The goal is to see if the drug can reduce these dangerous events compared to a placebo. Participants will be monitored for 16 weeks, with an option to continue in an open-label extension for about 32 more weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Centricity Research Morehead City Multispecialty

    Morehead City, North Carolina, 28557-3126, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195-0001, United States

  • Consano Clinical Research

    Shavano Park, Texas, 78231-1281, United States

  • Cotton-O'Neil Diabetes and Endocrinology Center

    Topeka, Kansas, 66606-2806, United States

  • Diabetes and Gandular Disease Clinic

    San Antonio, Texas, 78229-4801, United States

  • Duke Center for Metabolic and Weight Loss Surgery

    Durham, North Carolina, 27704-2726, United States

  • East Coast Institute for Research

    Jacksonville, Florida, 32216, United States

  • Endocrine and Psychiatry Center

    Houston, Texas, 77095-2856, United States

  • Georgia Clincal Research

    Lawrenceville, Georgia, 30044, United States

  • Hanson Diabetes Center

    Port Charlotte, Florida, 33952-6722, United States

  • Joslin Diabetes Center

    Boston, Massachusetts, 02215-5306, United States

  • NYC Health + Hospitals/Queens - BRANY

    New Hyde Park, New York, 11042-1214, United States

  • Penn Medicine University City

    Philadelphia, Pennsylvania, 19104, United States

  • Southern Endocrinology & Diabetes Associates

    Mesquite, Texas, 75149, United States

  • Stanford Health Care - Endocrinology Clinic

    Stanford, California, 94304, United States

  • Texas Valley Clinical Research, LLC

    Weslaco, Texas, 78596-7288, United States

  • UT Health San Antonio

    San Antonio, Texas, 78229-3931, United States

  • UWHealth - Junction Rd Medical Center Endocrinology Clinic

    Madison, Wisconsin, 53717-2656, United States

  • University of Colorado Health Anschutz Medical Campus

    Aurora, Colorado, 80045-2541, United States

  • Vanderbilt Weight Loss Center

    Nashville, Tennessee, 37212-3609, United States

Conditions

Explore the condition pages connected to this study.