Enterocolitis

This study looked at 170 extremely preterm infants (born at or before 27 weeks) to see if adding a human milk fortifier to all feedings early on helps them grow better and reduces a dangerous gut condition called necrotizing enterocolitis. One group received the fortifier as soon…

This study tested whether giving probiotics (single or multiple strains) to 249 premature babies for 28 days after birth could prevent necrotizing enterocolitis, sepsis, and improve growth. The babies were born before 36 weeks and weighed under 2500 grams. Researchers compared a …

This study tested whether giving a probiotic (Lactobacillus reuteri) to premature infants could reduce the risk of necrotizing enterocolitis (NEC), a severe gut infection, and death. One hundred babies born between 28 and 36 weeks and weighing 1000-2500 grams were enrolled. The p…

This study tested whether adding a bowel ultrasound to the standard abdominal X-ray helps doctors diagnose necrotizing enterocolitis (NEC) — a dangerous gut infection in premature babies — more accurately. Researchers enrolled 169 infants in the NICU and compared how quickly they…

This study tested whether adding lactase enzyme to milk feedings helps preterm babies (born before 34 weeks) digest better and gain weight. 124 infants received either lactase-supplemented or standard feedings for two weeks. Researchers tracked feeding tolerance, weight gain, and…

This completed study looked at 324 extremely low birth weight preterm infants (≤1250 grams) to see how anemia and red blood cell transfusions affect oxygen levels in their digestive tract. Researchers used a non-invasive device to measure tissue oxygen and collected blood, urine,…

This study looked at whether giving antibiotics early to extremely low birthweight babies (born before 31 weeks) might cause more harm than good. Researchers compared babies who got standard antibiotics to those who got a placebo. The goal was to see if early antibiotics increase…

This study looked back at the medical records of 400 newborns with necrotizing enterocolitis (NEC), a serious gut disease. Researchers wanted to see if combining blood test results and organ function scores could better predict which babies would develop a hole in their bowel or …

This study looked back at 118 newborns with necrotizing enterocolitis (NEC), a serious gut disease, to find early warning signs of severe complications or death. Researchers analyzed birth details, symptoms, blood tests, and organ function scores to see if combining these factors…

This pilot study tested whether computer models could predict sepsis and necrotizing enterocolitis (NEC) in very low birth weight infants (under 1500 grams). Researchers used existing NICU data to build and test these models. The goal was to see if this approach is feasible, not …

This study looked at 34 breastfed infants under 6 months old with cow's milk protein allergy. Researchers wanted to see if a cow's milk elimination diet for mothers and babies could improve symptoms, growth, and gut immune markers like MUC2 and sIgA. They collected stool samples …

This study looked at whether a simple stool test could help predict serious gut inflammation in premature babies. Researchers collected stool samples from 122 preterm infants born at 33 weeks or less, testing for a protein called calprotectin. The goal was to see if this test, co…

This study looks at whether a set of guidelines called the EMNODN NEC Care Bundle helps very preterm babies (born before 32 weeks) get more of their own mother's milk and reduces a life-threatening gut condition called necrotising enterocolitis (NEC). Researchers will compare dat…