Do early antibiotics harm fragile newborns? major trial investigates
NCT ID NCT03997266
First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 32 times
Summary
This study looked at whether giving antibiotics to extremely low birthweight babies in their first week of life leads to more health problems. The trial included 359 stable premature infants born between 23 and 30 weeks. Researchers compared babies who received antibiotics to those who got a placebo to see if there were differences in serious outcomes like late-onset infections, bowel disease, or death.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alfred I. duPont for Children of the Nemours Foundation
Philadelphia, Pennsylvania, 19107, United States
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Atrium Health Wake Forest Baptist
Winston-Salem, North Carolina, 27157, United States
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Golisano Children's Hospital at University of Rochester
Rochester, New York, 14642, United States
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Magee Womens Hospital
Pittsburgh, Pennsylvania, 15213, United States
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Maria Fareri Children's Hospital at Westchester Medical Center
Valhalla, New York, 10595, United States
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Penn State Medical College
Hershey, Pennsylvania, 17033, United States
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Pennsylvania Hospital/The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Sharp Mary Birch Hospital for Women & Newborns
San Diego, California, 92123, United States
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The Trustees of Columbia University in the City of New York
New York, New York, 10032-3702, United States
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USA Children's and Women's Hospital
Mobile, Alabama, 36688, United States
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University of Louisville Research Foundation Inc./Kosair Charities Pediatric Clinical Research Unit
Louisville, Kentucky, 40202, United States
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University of South Flordia Health
Tampa, Florida, 33606, United States
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University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229, United States
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Yale University School of Medicine
New Haven, Connecticut, 06520-8064, United States
Conditions
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